Protein Alignment Rab11 and RAB7A

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_004628.4
• Gene: RAB7A / 7879
• HGNCID: 9788
• Length: 207
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 64/163 - (39%)
• Similarity: 106/163 - (65%)
• Gaps: 6/163 - (3%)

  Fly    11 LFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQERYRA 75
            |.||:::|||||||::|::::...:|:.:.|:|||.:|.|:.:.||.:.:..||||||||||:::
Human     8 LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQS 72

  Fly    76 ITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHAD----QNIVIMLVGNKSDLRHLRSVPT 136
            :..|:||||...:||:|:....|::.::.|..|....|.    :|...:::|||.||.: |.|.|
Human    73 LGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLEN-RQVAT 136

  Fly   137 DEAKLFA-ERNGLSFIETSALDSTNVETAFQNI 168
            ..|:.:. .:|.:.:.||||.::.|||.|||.|
Human   137 KRAQAWCYSKNNIPYFETSAKEAINVEQAFQTI 169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	64/163 (39%)
RAB7A	NP_004628.4	Rab7	9..179	CDD:206655	63/162 (39%)
		Switch 1. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	28..41		2/12 (17%)
		Switch 2. /evidence=ECO:0000269|PubMed:15933719, ECO:0007744|PDB:1T91, ECO:0007744|PDB:1YHN	67..82		7/14 (50%)