Protein Alignment Rab11 and RAB6A

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_002860.2
• Gene: RAB6A / 5870
• HGNCID: 9786
• Length: 208
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 63/190 - (33%)
• Similarity: 115/190 - (60%)
• Gaps: 11/190 - (5%)

  Fly    12 FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQERYRAI 76
            ||:|.:|:..|||::|::||..:.|:...::|||::|.::::.::.:||:.|:||||||||:|::
Human    14 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIRLQLWDTAGQERFRSL 78

  Fly    77 TSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSVPTDEAKL 141
            ..:|.|.:..|::||||....:::...:|:.::|.....:::|||||||:||...|.|..:|.:.
Human    79 IPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGER 143

  Fly   142 FAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNVEPIDVK 201
            .|:...:.||||||....||:..|:.:...:..:.|.:.           .|..:.||:|
Human   144 KAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQD-----------RSREDMIDIK 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	58/160 (36%)
RAB6A	NP_002860.2	Rab6	14..174	CDD:206654	58/159 (36%)
		Switch 1. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	32..50		6/17 (35%)
		Switch 2. /evidence=ECO:0000269|PubMed:19141279, ECO:0007744|PDB:3CWZ	69..88		9/18 (50%)