Protein Alignment Rab11 and RAB3B

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_002858.2
• Gene: RAB3B / 5865
• HGNCID: 9778
• Length: 219
• Species: Homo sapiens
• Alignment Length: 182
• Identity: 73/182 - (40%)
• Similarity: 117/182 - (64%)
• Gaps: 0/182 - (0%)

  Fly     3 AREDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDT 67
            |.:..:||:||:::||:|.|||::.|.|:..:.|.....||:|::|..:::....|.:|.|||||
Human    14 ASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDT 78

  Fly    68 AGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLR 132
            |||||||.||:||||||:|.:|:|||....::..|:.|..:::.::..|..::|||||.|:...|
Human    79 AGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEER 143

  Fly   133 SVPTDEAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDP 184
            .|||::.:|.||:.|..|.|.||.::.:|..||:.::..|...:|.....||
Human   144 VVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDP 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	68/163 (42%)
RAB3B	NP_002858.2	Rab3	22..186	CDD:206657	67/163 (41%)
		Switch 1. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	45..58		4/12 (33%)
		Switch 2. /evidence=ECO:0000269|PubMed:35871249, ECO:0007744|PDB:8A4B	78..96		15/17 (88%)