Protein Alignment Rab11 and RAB3A

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_002857.1
• Gene: RAB3A / 5864
• HGNCID: 9777
• Length: 220
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 74/199 - (37%)
• Similarity: 119/199 - (59%)
• Gaps: 6/199 - (3%)

  Fly     5 EDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAG 69
            :..:||:||:::||:|.|||::.|.|:..:.|.....||:|::|..::|..:.|.||.|||||||
Human    16 DQNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAG 80

  Fly    70 QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSV 134
            |||||.||:||||||:|.:|:|||....::..|:.|..:::.::..|..::|||||.|:...|.|
Human    81 QERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVV 145

  Fly   135 PTDEAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQK-QIRDP-----PEGDVIRPS 193
            .::..:..|:..|..|.|.||.|:.||:..|:.::..|...:|:. ...||     .:|..:...
Human   146 SSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQLSDQ 210

  Fly   194 NVEP 197
            .|.|
Human   211 QVPP 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	67/163 (41%)
RAB3A	NP_002857.1	Rab3	22..186	CDD:206657	66/163 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		3/8 (38%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		13/15 (87%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..220		5/21 (24%)