Protein Alignment Rab11 and RAB2A

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_002856.1
• Gene: RAB2A / 5862
• HGNCID: 9763
• Length: 212
• Species: Homo sapiens
• Alignment Length: 189
• Identity: 97/189 - (51%)
• Similarity: 124/189 - (65%)
• Gaps: 2/189 - (1%)

  Fly     8 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQER 72
            |.||||.::|||:|||||.||.:||...|......||||||..|.|.:|||.||.|||||||||.
Human     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67

  Fly    73 YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSVPTD 137
            :|:||.:|||||.||||||||.:..|:.::..||.:.|.|::.|:||||:||||||...|.|..:
Human    68 FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKE 132

  Fly   138 EAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQK--QIRDPPEGDVIRPSN 194
            |.:.||..:||.|:||||..::|||.||.|...|||..:.:.  .|.:...|..|.|.:
Human   133 EGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQH 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	90/163 (55%)
RAB2A	NP_002856.1	PLN03108	1..188	CDD:178655	95/184 (52%)
		Required for interaction with PRKCI. /evidence=ECO:0000269|PubMed:14570876	2..19		10/15 (67%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		5/8 (63%)