DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab11 and RAB25

DIOPT Version :9

Sequence 1:	NP_477170.1	Gene:	Rab11 / 42501	FlyBaseID:	FBgn0015790	Length:	214	Species:	Drosophila melanogaster
Sequence 2:	NP_065120.2	Gene:	RAB25 / 57111	HGNCID:	18238	Length:	213	Species:	Homo sapiens

Alignment Length:	176	Identity:	120/176 - (68%)
Similarity:	151/176 - (85%)	Gaps:	0/176 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAG 69
            |::|:::|||||||:|||||:|||||||||||:.:|::||||||:||::.:....:|||||||||
Human     6 EEDYNFVFKVVLIGESGVGKTNLLSRFTRNEFSHDSRTTIGVEFSTRTVMLGTAAVKAQIWDTAG 70

  Fly    70 QERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSV 134
            .||||||||||||||||||||:|:.||.||..|||||:||.|||:..||:|||||||||...|.|
Human    71 LERYRAITSAYYRGAVGALLVFDLTKHQTYAVVERWLKELYDHAEATIVVMLVGNKSDLSQAREV 135

  Fly   135 PTDEAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQ 180
            ||:||::|||.|||.|:|||||||||||.||:.:|.||:..||:::
Human   136 PTEEARMFAENNGLLFLETSALDSTNVELAFETVLKEIFAKVSKQR 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	115/163 (71%)
RAB25	NP_065120.2	Rab11_like	11..174	CDD:206660	115/162 (71%)
RAB25	NP_065120.2	Effector region. /evidence=ECO:0000250	41..49		5/7 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0087
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1133775at2759
OrthoFinder	1	1.000	-	-		FOG0000259
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820