Protein Alignment Rab11 and RAB4B

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_057238.3
• Gene: RAB4B / 53916
• HGNCID: 9782
• Length: 213
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 97/206 - (47%)
• Similarity: 124/206 - (60%)
• Gaps: 19/206 - (9%)

  Fly     6 DEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQ 70
            :.||:|||.::||.:|.|||.||.:|..|:|..:|..||||||.:|.:.|.|||:|.||||||||
Human     3 ETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQ 67

  Fly    71 ERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSVP 135
            ||:|::|.:|||||.||||||||....||.::..||.:.|..|..|||::|.|||.||...|.|.
Human    68 ERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVT 132

  Fly   136 TDEAKLFAERNGLSFIETSALDSTNVETAF----QNILTEI---------------YRIVSQKQI 181
            ..||..||:.|.|.|:|||||...|||.||    :.||.:|               |...|.:|:
Human   133 FLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDASLRQL 197

  Fly   182 RDPPEGDVIRP 192
            |.|.....:.|
Human   198 RQPRSAQAVAP 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	90/182 (49%)
RAB4B	NP_057238.3	Rab4	9..169	CDD:206696	85/159 (53%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	39..44		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	65..74		6/8 (75%)