Protein Alignment Rab11 and RAB8B

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_057614.1
• Gene: RAB8B / 51762
• HGNCID: 30273
• Length: 207
• Species: Homo sapiens
• Alignment Length: 171
• Identity: 87/171 - (50%)
• Similarity: 122/171 - (71%)
• Gaps: 4/171 - (2%)

  Fly     8 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQER 72
            ||||||::|||||||||:.||.||:.:.||....||||::|..|:||:|||.||.||||||||||
Human     5 YDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQER 69

  Fly    73 YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRHLRSVPTD 137
            :|.||:||||||:|.:|||||....:::|::.|:|.:.:||..::..|::|||.|:...|.|..:
Human    70 FRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQVSKE 134

  Fly   138 EAKLFAERNGLSFIETSALDSTNVETAF----QNILTEIYR 174
            ..:..|...|:.|:||||..|.|||.||    ::|:|::.|
Human   135 RGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNR 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	85/167 (51%)
RAB8B	NP_057614.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	84/165 (51%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		6/13 (46%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		13/16 (81%)