Protein Alignment Rab11 and RAB7B

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_796377.3
• Gene: RAB7B / 338382
• HGNCID: 30513
• Length: 199
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 60/204 - (29%)
• Similarity: 111/204 - (54%)
• Gaps: 17/204 - (8%)

  Fly    13 KVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIWDTAGQERYRAIT 77
            |::::|..||||::||.::....|..|.::|:|....::.|.:...|:|.|||||.||||:|::.
Human    10 KLIIVGAIGVGKTSLLHQYVHKTFYEEYQTTLGASILSKIIILGDTTLKLQIWDTGGQERFRSMV 74

  Fly    78 SAYYRGAVGALLVYDIAKHLTYENVERWLRELRDH---ADQNIVIMLVGNKSDLRHLRSVPTDEA 139
            |.:|:|:.|.:|.:|:....::|.::.|..::...   .:|:..::|:|||.||.. |.||.:.|
Human    75 STFYKGSDGCILAFDVTDLESFEALDIWRGDVLAKIVPMEQSYPMVLLGNKIDLAD-RKVPQEVA 138

  Fly   140 KLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNVEPIDVKPTV 204
            :.:.....:.:.|.||.:..||..||:.:.:   |.:|:.|       .::.....|.|.:.|..
Human   139 QGWCREKDIPYFEVSAKNDINVVQAFEMLAS---RALSRYQ-------SILENHLTESIKLSPDQ 193

  Fly   205 TADVRKQCC 213
            :   |.:||
Human   194 S---RSRCC 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	51/162 (31%)
RAB7B	NP_796377.3	Rab	9..169	CDD:206640	51/159 (32%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P51149	28..41		2/12 (17%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P51149	67..82		7/14 (50%)