Protein Alignment Rab11 and RAB31

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_006859.2
• Gene: RAB31 / 11031
• HGNCID: 9771
• Length: 195
• Species: Homo sapiens
• Alignment Length: 213
• Identity: 82/213 - (38%)
• Similarity: 124/213 - (58%)
• Gaps: 19/213 - (8%)

  Fly     1 MGAREDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKTIKAQIW 65
            |..||      .||.|:||:|||||:::.||.::.|:.....|||..|.|:::....:..|..||
Human     2 MAIRE------LKVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIW 60

  Fly    66 DTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLRELRDHADQNIVIMLVGNKSDLRH 130
            |||||||:.::...||||:..|::||||.|..::..:::|::||::|..:|||:.:.|||.||..
Human    61 DTAGQERFHSLAPMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNKCDLSD 125

  Fly   131 LRSVPTDEAKLFAERNGLSFIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNV 195
            :|.||..:||.:||..|...:||||.::.|:|..||.|..:|..:       ||.|........|
Human   126 IREVPLKDAKEYAESIGAIVVETSAKNAINIEELFQGISRQIPPL-------DPHENGNNGTIKV 183

  Fly   196 EPIDVKPTVTADVRKQCC 213
            |    |||:.|.  ::||
Human   184 E----KPTMQAS--RRCC 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	67/163 (41%)
RAB31	NP_006859.2	Rab5_related	6..168	CDD:206653	68/167 (41%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	30..42		4/11 (36%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	63..79		8/15 (53%)