Protein Alignment Rab11 and RAB32

DIOPT Version :10

• Sequence 1: NP_477170.1
• Gene: Rab11 / 42501
• FlyBaseID: FBgn0015790
• Length: 214
• Species: Drosophila melanogaster
• Sequence 2: NP_006825.1
• Gene: RAB32 / 10981
• HGNCID: 9772
• Length: 225
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 71/212 - (33%)
• Similarity: 126/212 - (59%)
• Gaps: 16/212 - (7%)

  Fly     9 DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIEVDGKT-IKAQIWDTAGQER 72
            ::||||::||:.||||::::.|:....|:...::||||:||.:.:..|.:| ::.|:||.|||||
Human    23 EHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQER 87

  Fly    73 YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLREL--RDHADQN--IVIMLVGNKSDLRHLRS 133
            :..:|..||:.||||.:|:||::..|:|.|.:|..:|  :.|....  |..:|:.||.|.....|
Human    88 FGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANKCDQNKDSS 152

  Fly   134 VPTDEAKLFAERNGLS-FIETSALDSTNVETAFQNILTEIYRIVSQKQIRDPPEGDVIRPSNVEP 197
            ....:...|.:.:|.: :.||||.|:.|:|.|.:.::.:|  :|:.:..  |.|     .::|:.
Human   153 QSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKI--LVNHQSF--PNE-----ENDVDK 208

  Fly   198 IDV-KPTVTADVRKQCC 213
            |.: :.|:.|:.:.|||
Human   209 IKLDQETLRAENKSQCC 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab11	NP_477170.1	Rab11_like	9..173	CDD:206660	60/169 (36%)
RAB32	NP_006825.1	Rab32_Rab38	26..224	CDD:206692	67/206 (33%)
		Switch 1. /evidence=ECO:0000269|PubMed:24856514, ECO:0007744|PDB:4CYM, ECO:0007744|PDB:4CZ2	48..62		5/13 (38%)
		Switch 2. /evidence=ECO:0000269|PubMed:24856514, ECO:0007744|PDB:4CYM, ECO:0007744|PDB:4CZ2	84..97		6/12 (50%)
		PKA-RII subunit binding domain	178..197		5/20 (25%)