Protein Alignment rtet and QDR2

DIOPT Version :10

• Sequence 1: NP_524429.1
• Gene: rtet / 42500
• FlyBaseID: FBgn0028468
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_012145.1
• Gene: QDR2 / 854685
• SGDID: S000001383
• Length: 542
• Species: Saccharomyces cerevisiae
• Alignment Length: 532
• Identity: 119/532 - (22%)
• Similarity: 194/532 - (36%)
• Gaps: 166/532 - (31%)

  Fly    29 NNKALDKEASENGKPEKSDPMIYI--------IFVSLLFDLLAFTIILPLLPSLLEHYRQNDSSG 85
            |.:..||.|....:..|.:|.|..        .|.::|....|||.....:...:
Yeast    26 NRETADKLALTRTESVKPEPEITAPPHSRFSRSFKTVLIAQCAFTGFFSTIAGAI---------- 80

  Fly    86 LYAVLTDRVRWF---QQLLGAPDRYISVLFGGFLGSMFSFLQFVASPIVGGLSDYYGRKPVLL-- 145
            .|.||:...|.|   ::|:.     ::|:       ::...|.:|...:||.:|..||:||:|
Yeast    81 YYPVLSVIERKFDIDEELVN-----VTVV-------VYFVFQGLAPTFMGGFADSLGRRPVVLVA 133

  Fly   146 ------ACASGIALSYLIWACSSNFALFVLARFV--GGISKGNISLCMSVITDVSSVKTRG---- 198
                  ||   |.|     ||:..:|..::.|.:  .|||. .|::...::.||::...||
Yeast   134 IVIYFGAC---IGL-----ACAQTYAQIIVLRCLQAAGISP-VIAINSGIMGDVTTRAERGGYVG 189

  Fly   199 --RGMALVGVAFSLGFIVGPMIGALF---AIFSDKSGSTWFVLPSLLAFGLAVGD-LVVLACCLR 257
              .|..::|.||  |.::|..:.:.:   |||       ||         ||:|. :..||..|
Yeast   190 YVAGFQVLGSAF--GALIGAGLSSRWGWRAIF-------WF---------LAIGSGICFLASFL- 235

  Fly   258 ETLPKEKRVKEIS-----SALSYGLQLLNFSAIFRFAAIKNVPKKD---------------IAAL 302
             .||:.||  .||     :..||    ||.:.|.....::.....|               :|..
Yeast   236 -ILPETKR--NISGNGSVTPKSY----LNRAPILVLPTVRKSLHLDNPDYETLELPTQLNLLAPF 293

  Fly   303 RSIGLVYFLYLFLYSGLEF-----------TVTFLMYH----KFGYTSMDQAKMFLTTGVI---- 348
            :.:.......|.|.:||:|           |.....||    |.|...:......|.:.||
Yeast   294 KILKAYEICILMLVAGLQFAMYTTHLTALSTALSKQYHLTVAKVGLCYLPSGICTLCSIVIAGRY 358

  Fly   349 --------------------MTLLQG-----SVVRRLPEAKIK-GYAIFSLYLIVPAFVVVGLAE 387
                                ..||:.     ::|:|:.|...| .:.||...| .||||.:.|:.
Yeast   359 LNWNYRRRLKYYQNWLGKKRSKLLEEHDNDLNLVQRIIENDPKYTFNIFKARL-QPAFVTLLLSS 422

  Fly   388 GSRMLYAGMTLFAISTAFAVTCLTTLVSKYGNDDQKGS---VLGIFRSLGALARALGPVVGCI-A 448
            .....| |..:...:...||.|::...|.:.|.....|   ::.:|.:..:.|      .||: .
Yeast   423 SGFCAY-GWCITVKAPLAAVLCMSGFASLFSNCILTFSTTLIVDLFPTKTSTA------TGCLNL 480

  Fly   449 FWCVGSRITYIA 460
            |.|:.|.: :||
Yeast   481 FRCILSAV-FIA 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rtet	NP_524429.1	MFS_MFSD10	50..476	CDD:340947	113/511 (22%)
QDR2	NP_012145.1	MFS_Tpo1_MDR_like	64..530	CDD:340881	110/494 (22%)