Protein Alignment rtet and AZR1

DIOPT Version :10

• Sequence 1: NP_524429.1
• Gene: rtet / 42500
• FlyBaseID: FBgn0028468
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_011740.3
• Gene: AZR1 / 853139
• SGDID: S000003456
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 495
• Identity: 92/495 - (18%)
• Similarity: 186/495 - (37%)
• Gaps: 130/495 - (26%)

  Fly     7 RHNGTAAMEKQSHSQTGSHHHNNNKALDKEASENGKPEKSDPMIYIIFVSLLFDLLAFTIILPLL 71
            |.|.|.:..||          |.:..|:..|||:.:..|.. ::|...::|...|....:.:.::
Yeast    34 RRNSTQSTSKQ----------NVSVVLEDNASESNELPKGF-ILYASLIALALSLFLAALDIMIV 87

  Fly    72 PSLLEHYRQNDSSGLYAVLTDRVRWFQQLLGAPDRYISVLFGGFLGSMFSFLQFVASPIVGGLSD 136
            .:::|...:  ..|.|:    .:.|.......|:..:::::|.           :|:||
Yeast    88 STIIEEVAK--QFGSYS----EIGWLFTGYSLPNALLALIWGR-----------IATPI------ 129

  Fly   137 YYGRKPVLLACASGIALSYLIWACSSNFALFVLARFVGGISKGNI-SLCMSVITDVSSVKTRGRG 200
              |.|..:|.......:..||.|.:::.::.:..|.:.|:....| ||...:.:.:.....||..
Yeast   130 --GFKETMLFAIVIFEIGSLISALANSMSMLIGGRVIAGVGGCGIQSLSFVIGSTLVEESQRGIL 192

  Fly   201 MALVGVAFSLGFIVGPMIGALFAIFSDKSGSTW--------------------FVLPSLLAFGLA 245
            :|::..:|::..:|||.:|.:|.     |..||                    |..|.|..|
Yeast   193 IAVLSCSFAIASVVGPFLGGVFT-----SSVTWRWCFYVNLPIGGLAFFLFLFFYNPGLSTF--- 249

  Fly   246 VGDLVVLACCLRETLPKEKRVK----EISSALSYG-LQLLNFSAIFRFAAIKNVPKKDIAALRSI 305
                       :||:...::..    ||...::|. |::..||.:       |..:|....|.
Yeast   250 -----------QETMDNIRKFPSQFIEIVRNVAYHLLKIKGFSKL-------NGWRKPFMELI-- 294

  Fly   306 GLVYFLYLFLYSGLEFTVTFLMY----HKFGYTSMDQAKMFLTTGVIMTLLQGSVVRRLPEAKIK 366
             .:|.:..|::....||...|.:    :::.:.|.....:|: .|:::.:|.|
Yeast   295 -FMYDIIEFVFCSAGFTCILLAFTFGGNRYAWNSASIIILFI-IGIVLVVLAG------------ 345

  Fly   367 GYAIFSLYLIVPAFVVVGLAEGSRMLYAGMT-----LFAISTAFAVTCLTTLVSKYGNDDQKGSV 426
               |:. :|:.|.|.:|......:.|.:...     :|.::.|..:||.       |...|...:
Yeast   346 ---IYD-FLVFPKFNIVKATPHYQPLMSWTNIKKPGIFTVNIALFLTCA-------GYISQFTYI 399

  Fly   427 LGIFRSL--GALARALGPVVGCIAFWCVGSRITYIAGGLL 464
            :..|:.:  .:..||...:|.||    :.:.:|.|..|.:
Yeast   400 VQYFQLIYNDSAWRAAVHLVACI----ISTVVTAILCGAI 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rtet	NP_524429.1	MFS_MFSD10	50..476	CDD:340947	81/452 (18%)
AZR1	NP_011740.3	MFS_Azr1_MDR_like	83..540	CDD:341045	78/435 (18%)