Protein Alignment rtet and MFSD10

DIOPT Version :10

• Sequence 1: NP_524429.1
• Gene: rtet / 42500
• FlyBaseID: FBgn0028468
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_001397632.1
• Gene: MFSD10 / 10227
• HGNCID: 16894
• Length: 480
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 188/422 - (44%)
• Similarity: 268/422 - (63%)
• Gaps: 26/422 - (6%)

  Fly    43 PEKSDPMIYIIFVSLLFDLLAFTIILPLLPSLLE-HYRQNDSSGLYAVLTDRVRWFQQLLGAP-- 104
            ||:.  ::.::|:.||.||||||::|||||.||| |.|.:|.  ||......|.||...:|.|
Human    20 PERR--VVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDP--LYGSWQGGVDWFATAIGMPVE 80

  Fly   105 DRYISVLFGGFLGSMFSFLQFVASPIVGGLSDYYGRKPVLLACASGIALSYLIWACSSNFALFVL 169
            .||.||||||.:||.||.|||:.:|:.|..||..||:||:|.|..|:|.||.:||.|.:||.|:.
Human    81 KRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLA 145

  Fly   170 ARFVGGISKGNISLCMSVITDVSSVKTRGRGMALVGVAFSLGFIVGPMIGALFAIFSDKSGSTWF 234
            :|.:|||||||:||..:::.|:.|...|.:|||::||||||||.:|||:||...:    ..:.||
Human   146 SRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPL----EMAPWF 206

  Fly   235 VLPSLLAFGLAVGDLVVLACCLRETLPKEKRVKEISSALSYGLQLLNFSAIFRFAAI---KNVPK 296
            .|.      .|..||:.:.|.|.||||.|||...|:........||:..|:.||:|:   ::.|.
Human   207 ALL------FAASDLLFIFCFLPETLPLEKRAPSIALGFRDAADLLSPLALLRFSAVARGQDPPS 265

  Fly   297 KD-IAALRSIGLVYFLYLFLYSGLEFTVTFLMYHKFGYTSMDQAKMFLTTGVIMTLLQGSVVRRL 360
            .| :::||.:||||||||||:||||:|::||.:.:|.::|:.|.|||...|:.|..:||:..||:
Human   266 GDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRI 330

  Fly   361 -PEAKIKGYAIFSLYLIVPAFVVVGLAEGSRMLYAGMTLFAISTAFAVTCLTTLVSKYGNDDQKG 424
             |..::.... .:|.|:||||:::|......:|..|:.|::.:.|..|.||:::|:.||:..|||
Human   331 HPGGEVAAVK-RALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKG 394

  Fly   425 SVLGIFRSLGALARALGPVV---GCIAFWCVG 453
            :|:|..|||||||||.||:|   |..|.||.|
Human   395 TVMGTLRSLGALARAAGPLVAASGEGAGWCWG 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rtet	NP_524429.1	MFS_MFSD10	50..476	CDD:340947	186/415 (45%)
MFSD10	NP_001397632.1	MFS	51..426	CDD:475125	169/387 (44%)