Protein Alignment Sec15 and Exoc6b

DIOPT Version :10

• Sequence 1: NP_650942.1
• Gene: Sec15 / 42499
• FlyBaseID: FBgn0266674
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: XP_036008283.1
• Gene: Exoc6b / 75914
• MGIID: 1923164
• Length: 814
• Species: Mus musculus
• Alignment Length: 788
• Identity: 336/788 - (42%)
• Similarity: 499/788 - (63%)
• Gaps: 36/788 - (4%)

  Fly     6 VQDIEAVDDYW-GPTFRSILEGNNTKQIGDQLEQRIRSHDKEIERICNLYYQGFIDSIQELLQVR 69
            :::||:.|... |||.||:.:|....:..::||.|||:||:|||::||.:||||:|||.|||:||
Mouse    21 LREIESTDTACIGPTLRSVYDGEEHGRFMEKLETRIRNHDREIEKMCNFHYQGFVDSITELLKVR 85

  Fly    70 TQAQQLHNEVHSLDTSLRQISASLIQQGNDLVRARQIESNLASAIEALKSCLPALECYMKFTQQA 134
            .:||:|.|:|...:..|:.....|:....:|.:.|..:.|:::.::.|..|||.||.|.|...|.
Mouse    86 GEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISATVDKLMLCLPVLEMYSKLRDQM 150

  Fly   135 KNKQYYQALRTLETLETEHLTRLKTHNYRFATQMQIQIPIIKENIRRSSASDFREFLENIRKFSP 199
            |.|::|.||:|||.||..:|.::.  :|||...|...||.::|.|:..|.||.::|||:|||.|.
Mouse   151 KTKRHYPALKTLEHLEHTYLPQVS--HYRFCKVMVDNIPKLREEIKDVSMSDLKDFLESIRKHSD 213

  Fly   200 RIGELAITHTKQ--------LQ----------KRDINAIIAEHMQQMNGGEAGGAG----AGGDD 242
            :|||.|:...:|        ||          |:|:..|....::..:......:|    ...:|
Mouse   214 KIGETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDVYTIFDAEVESTSPKSEQDSGILDVEDEED 278

  Fly   243 DGANVSAQDLIDFSPIYRCLHIYMVLGQREYFEKDYRQQRRDQAKLVLQPPPNMHDNLEAYKTYI 307
            |.....||||:||||:|||||||.|||.||.||..||:|||.||:||||||.|||:.|:.|:.|.
Mouse   279 DEEVPGAQDLVDFSPVYRCLHIYSVLGARETFENYYRKQRRKQARLVLQPPSNMHETLDGYRKYF 343

  Fly   308 CAIVGFFVVEDHVKNTAGDVVTSSYLEDLWSSSLTKFVNEISMSSSSCTDPNILLRIKNLIMLSI 372
            ..||||||||||:.:|...:|..:|:::||..:|:|.:..:...||.|:|||::|.:||||:|..
Mouse   344 NQIVGFFVVEDHILHTTQGLVNRAYIDELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFA 408

  Fly   373 NTFKCYGYTVNILWELLHNMRDHYNEVLLQRWVHVFREILDKEQFLPMVVQNTEEYECIIERFPF 437
            :|.:.||:.||.|:::|..:||.|:|.||::|..|||.|||.:.:.|:.|.:.|.|:.::.:|||
Mouse   409 DTLQVYGFPVNQLFDMLLEIRDQYSETLLKKWAGVFRNILDSDNYSPIPVTSEETYKKVVGQFPF 473

  Fly   438 HSEQLENAPFPKKFPFSRMVPEVYHQAKEFMYACMKFAEELTLSPNEVAAMVRKAANLLLTRSFS 502
            ...:||..|||||||||..||:||:|.|||:|||:||:|:|.||..||..|:||:.||||||:.|
Mouse   474 QDIELEKQPFPKKFPFSEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLS 538

  Fly   503 GCLSVVFRQPSITLTQLIQIIIDTQYLEKAGPFLDEFVCHMTN----TERSVSQTPSAMFHVARQ 563
            ..|..|.::.:|.||:|:||||:|.:|||:..:|:||:.::||    |..:.....:..|..||.
Mouse   539 NSLQNVIKRKNIGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDARH 603

  Fly   564 DAEKQVGLRICSKIDEFFELSAYDWLLVEPPGIASAFITDMISYLKSTFDSFAFKLPHIAQAACR 628
            .||:::...:..|||:|.:|:.|||:..:....||.::.|:|::|:|||..|......:||.||.
Mouse   604 AAEEEIYTNLNQKIDQFLQLADYDWMTGDLDNKASDYLVDLIAFLRSTFAVFTHLPGKVAQTACM 668

  Fly   629 RTFEHIAEKIYSIMYDEDVKQISTGALTQINLDLMQCEFFAASEPVPGLKEGELSKYFLRNRQLL 693
            ...:|:|..:..::.:.:|:|::.|||.|.|||:.:||.||.|.||||.:|..|...|:..||||
Mouse   669 SACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDLRQLL 733

  Fly   694 DLLILEEWSTYFHDYGKQENRYHLVQPQSIIVILEKI-RE----ADKKPIFSLVRKN--DKKKLL 751
            ||.|..:||||..|||:...:|..|.|.:.:.:|||: ||    :.|..:|:..|||  ||:||:
Mouse   734 DLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKLSREMKDTSRKNNMFAQFRKNERDKQKLI 798

  Fly   752 ETVLKQLK 759
            :||.|||:
Mouse   799 DTVAKQLR 806

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec15	NP_650942.1	Sec15	428..730	CDD:461169	132/305 (43%)
Exoc6b	XP_036008283.1	Sec15	464..770	CDD:461169	132/305 (43%)