Protein Alignment Sec15 and Exoc6

DIOPT Version :10

• Sequence 1: NP_650942.1
• Gene: Sec15 / 42499
• FlyBaseID: FBgn0266674
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_062150.2
• Gene: Exoc6 / 50556
• RGDID: 3653
• Length: 804
• Species: Rattus norvegicus
• Alignment Length: 789
• Identity: 321/789 - (40%)
• Similarity: 495/789 - (62%)
• Gaps: 47/789 - (5%)

  Fly     6 VQDIEAVDDYW-GPTFRSILEG--NNTKQIGDQLEQRIRSHDKEIERICNLYYQGFIDSIQELLQ 67
            :|:||:.|... |||.||:.:|  |..|:..::|:..||:||||||::||.::|||:|:|.|||:
  Rat    18 LQEIESTDTACVGPTLRSVYDGQPNAHKKFMEKLDACIRNHDKEIEKMCNFHHQGFVDAITELLK 82

  Fly    68 VRTQAQQLHNEVHSLDTSLRQISASLIQQGNDLVRARQIESNLASAIEALKSCLPALECYMKFTQ 132
            ||..|::|..:|...:...:.....:|:|..|::|.|..:.|:.:.:|.|:.|||.||.|.|..:
  Rat    83 VRADAEKLKVQVTDTNRRFQDAGKEVIEQTEDIIRCRIQQRNITTVVEKLQLCLPVLEMYSKLKE 147

  Fly   133 QAKNKQYYQALRTLETLETEHLTRLKTHNYRFATQMQIQIPIIKENIRRSSASDFREFLENIRKF 197
            |...::||.||:|:|.||..:..|:.  .|||...|...:|.::|:|:..|.||.::|||:|||.
  Rat   148 QMSMQRYYSALKTMEQLENVYFPRVS--QYRFCQLMMDTLPKLREDIKDISMSDLKDFLESIRKH 210

  Fly   198 SPRIGELAITHTKQLQKRDINAIIAEHMQQMNGG-------------------------EAGGAG 237
            |.:|||.|:   ||.|::...:|..:....|..|                         ||
  Rat   211 SDKIGETAM---KQAQQQKSFSIAVQKQTNMRFGKNMHVNNDRTLEEKSDIILKHTLEEEA---- 268

  Fly   238 AGGDDDGANVSAQDLIDFSPIYRCLHIYMVLGQREYFEKDYRQQRRDQAKLVLQPPPNMHDNLEA 302
               ::|...::.|||:||||:|||.|||..||..|.||..||:||:.||:|||||..::|:.::.
  Rat   269 ---ENDEEVLTVQDLVDFSPVYRCSHIYSALGDEETFENYYRKQRKKQARLVLQPQSSVHETVDG 330

  Fly   303 YKTYICAIVGFFVVEDHVKNTAGDVVTSSYLEDLWSSSLTKFVNEISMSSSSCTDPNILLRIKNL 367
            |:.|...||||||||||:.:....:||.:|.::||:.:|:|.:..:...||.||||:::|.:|||
  Rat   331 YRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNL 395

  Fly   368 IMLSINTFKCYGYTVNILWELLHNMRDHYNEVLLQRWVHVFREILDKEQFLPMVVQNTEEYECII 432
            |::..:|.:.||::||.|::||..:||.|||.||::|..:||:|.:::.:.|:.:.:.|||:.:|
  Rat   396 IVIFADTLQGYGFSVNRLFDLLFEIRDQYNETLLKKWAGIFRDIFEEDNYSPIPIGSEEEYKMVI 460

  Fly   433 ERFPFHSEQLENAPFPKKFPFSRMVPEVYHQAKEFMYACMKFAEELTLSPNEVAAMVRKAANLLL 497
            .:|||....||...||||||.|:.||.:|.|.|||:||.:||:|.|..|..|:..|:||:.||||
  Rat   461 SKFPFQDPDLEKQSFPKKFPMSQSVPLIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLL 525

  Fly   498 TRSFSGCLSVVFRQPSITLTQLIQIIIDTQYLEKAGPFLDEFVCHMTNTERSVSQTPS----AMF 558
            ||..|.||..:.|:|.|.||:|:||||:|.:||:|..:|::|:.::||..:....|..    :.|
  Rat   526 TRILSSCLLNLIRKPHIGLTELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTF 590

  Fly   559 HVARQDAEKQVGLRICSKIDEFFELSAYDWLLVEPPGIASAFITDMISYLKSTFDSFAFKLPHIA 623
            ..||..||.::..::..|||||.:|:.|||.:.|..|.||.::.|:|::|:|.|..|......:|
  Rat   591 KDARHAAEGEIYTKLNQKIDEFVQLADYDWTMAESDGRASGYLMDLINFLRSIFQVFTHLPGKVA 655

  Fly   624 QAACRRTFEHIAEKIYSIMYDEDVKQISTGALTQINLDLMQCEFFAASEPVPGLKEGELSKYFLR 688
            |.||....:|::..:..::.|.::||||.||:.|.|||::|||.||:||||||.:...|...|:.
  Rat   656 QTACMSACQHLSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFID 720

  Fly   689 NRQLLDLLILEEWSTYFHDYGKQENRYHLVQPQSIIVILEKIREADKK-PIFSLVRKN--DKKKL 750
            .||||||.::.:||||..|||:..::|..|.|.:.:.:|||:::..|| .||:..|||  |::||
  Rat   721 LRQLLDLFMVWDWSTYLADYGQPASKYLRVNPHAALTLLEKMKDTSKKNNIFAQFRKNDRDRQKL 785

  Fly   751 LETVLKQLK 759
            :|||:|||:
  Rat   786 IETVVKQLR 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec15	NP_650942.1	Sec15	428..730	CDD:461169	131/305 (43%)
Exoc6	NP_062150.2	Sec15	456..762	CDD:461169	131/305 (43%)