DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5745 and AT2G30710

DIOPT Version :9

Sequence 1:	NP_650941.3	Gene:	CG5745 / 42498	FlyBaseID:	FBgn0038855	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_565706.1	Gene:	AT2G30710 / 817622	AraportID:	AT2G30710	Length:	440	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	186/499 - (37%)
Similarity:	266/499 - (53%)	Gaps:	86/499 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 NSSTFWKNSGRRVPGRPSPKRELEKAAAVGVAVGRGAAPGSGMVSTFTEYQKSVSDAWDMGDDEF 112
            |...|.|  ||.:||:              |.:.|.:.|....:|  ..||:|:|:. |.|.:|.
plant    22 NVQGFLK--GRSIPGK--------------VLLTRRSDPPPYPIS--PTYQRSLSEN-DAGRNEL 67

  Fly   113 CIISSTEAAAAAVGAGDAAHFSRQVSQTVALNVIETHSRSNQNHNASRSANESGADLVPVSSSST 177
                                |...|..              ::||:|:..:.:.|..:..:||:.
plant    68 --------------------FESPVEV--------------EDHNSSKKHDNTYAGKLRSNSSAE 98

  Fly   178 DDCKEDRRSLPDSNENRSRLRNYPGRPQLQKISSNCQDSEYETKIEKFQVVLDSPQLDLVALKKI 242
            ...||                     .|..||.....||   .::.||..||....:.|..|:::
plant    99 RSVKE---------------------VQNLKIGVRSSDS---ARVMKFNKVLSETTVILEKLREL 139

  Fly   243 SWSGVPRKMRAVSWRLLSKYLPPSSERRMAVLESKRQGYQDLRHNYFRVDSQDETQQD----TYR 303
            :|:|||..||...||||..|.||:|:||.|||..||..|.:....::  |..|..:.|    ..|
plant   140 AWNGVPHYMRPDVWRLLLGYAPPNSDRREAVLRRKRLEYLESVGQFY--DLPDSERSDDEINMLR 202

  Fly   304 QIHIDVPRMNPQIPLFQQQLVQEMFERILFIWAIRHPASGYVQGINDLVTPFFIVFLQEALTPNT 368
            ||.:|.||..|.:..|||:.||:..||||:.|||||||||||||||||||||.::||.|.|....
plant   203 QIAVDCPRTVPDVSFFQQEQVQKSLERILYTWAIRHPASGYVQGINDLVTPFLVIFLSEYLDGGV 267

  Fly   369 DLEKYDMSTLPEETRNIIEADSFWCLSKFLDCIQDNYIFAQLGIQEKVNQLKDLIQRIDVNLHRH 433
            |  .:.|..|..|..:.:|||.:|||:|.||.:||:|.|||.|||..|.:||:|::|||..:.||
plant   268 D--SWSMDDLSAEKVSDVEADCYWCLTKLLDGMQDHYTFAQPGIQRLVFKLKELVRRIDEPVSRH 330

  Fly   434 LQAHGVDYLQFSFRWMNNLLTRELPLHCTIRLWDTYLAESDGFALFHLYVCAAFLLHWKEQLMQQ 498
            ::.||:::|||:|||.|.||.||:|.:...|||||||||.|....|.:|:.|:|||.|.::| ::
plant   331 MEEHGLEFLQFAFRWYNCLLIREIPFNLINRLWDTYLAEGDALPDFLVYIYASFLLTWSDEL-KK 394

  Fly   499 NDFQGLMLLLQNLPTHNWSDRQINVLLAEAFRLKFTYADAPKHL 542
            .|||.:::.||:||||||||:::.::|:.|:.....:.::|.||
plant   395 LDFQEMVMFLQHLPTHNWSDQELEMVLSRAYMWHSMFNNSPNHL 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5745	NP_650941.3	TBC	243..496	CDD:214540	128/256 (50%)
AT2G30710	NP_565706.1	COG5210	14..439	CDD:227535	186/499 (37%)
AT2G30710	NP_565706.1	RabGAP-TBC	200..392	CDD:366170	103/193 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	243	1.000	Domainoid score	I570
eggNOG	1	0.900	-	-		E1_KOG1092
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H23043
Inparanoid	1	1.050	306	1.000	Inparanoid score	I755
OMA	1	1.010	-	-		QHG54276
OrthoDB	1	1.010	-	-		D750722at2759
OrthoFinder	1	1.000	-	-		FOG0002429
OrthoInspector	1	1.000	-	-		oto3531
orthoMCL	1	0.900	-	-		OOG6_101452
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1614
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840