Protein Alignment Tbc1d22 and tbc1d2b

DIOPT Version :10

• Sequence 1: NP_650941.3
• Gene: Tbc1d22 / 42498
• FlyBaseID: FBgn0038855
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: XP_012822167.2
• Gene: tbc1d2b / 734055
• XenbaseID: XB-GENE-5932742
• Length: 944
• Species: Xenopus tropicalis
• Alignment Length: 338
• Identity: 72/338 - (21%)
• Similarity: 114/338 - (33%)
• Gaps: 93/338 - (27%)

  Fly   214 QDSEYETKIEKFQVVLDSPQLDLVALKKIS----W-----------------------SGVPRKM 251
            :|.|.|.|:......||...|.|...::||    |                       :|:|.:.
 Frog   584 EDDEEEEKLVAKVRALDLKTLSLTENQEISNVVKWDNYFASTVNREMACSPELKALVRNGIPHEH 648

  Fly   252 RAVSWRLLSKYLPPSSERRMAVLESKR------QGY-QDLRHNYFRVDSQDETQQDTYRQIHIDV 309
            |:..|:..:.            |..|:      .|| |.|..|..      |.|....:||.:|:
 Frog   649 RSRMWKWFTN------------LHIKKLKDEAAPGYFQSLLQNAL------EKQNPASKQIELDL 695

  Fly   310 PRMNPQIPLFQQQLVQ--EMFERILFIWAIRHPASGYVQGINDLVTPFFIVFLQEALTPNTDLEK 372
            .|..|....:.....:  :....:|..::.|:|..||.||||.|.....:...||
 Frog   696 MRTLPNNKHYTSPTSEGIQKLRNVLLAYSWRNPDIGYCQGINRLAAIALLYLDQE---------- 750

  Fly   373 YDMSTLPEETRNIIEADSFWCLSKFLDCI--QDNYIFAQLGIQEKVNQLKDLIQRIDVNLHRHLQ 435
                            |:||||...::..  :|.|....||.|......|||:......|..|.:
 Frog   751 ----------------DAFWCLVTIVEAFMPRDYYTKTLLGSQVDQRVFKDLMNEKLPRLCAHFE 799

  Fly   436 AHGVDYLQFSFRWMNNLLTRELPLHCTIRLWDTYLAESD----GFALFHLYVCAAFLLHWKEQLM 496
            .:.|||...:|.|...:....:......|:||:.|.|..    .|||       ....:.:|:::
 Frog   800 QYKVDYTLITFNWFLVVFVDSVVSDILFRIWDSLLYEGSKVIFRFAL-------GLFKYKEEEIL 857

  Fly   497 QQNDFQGLMLLLQ 509
            :..|...:...|:
 Frog   858 KLQDSMSIFKYLR 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d22	NP_650941.3	TBC	243..496	CDD:214540	61/294 (21%)
tbc1d2b	XP_012822167.2	PH_TBC1D2A	34..134	CDD:269966
		Smc	322..>560	CDD:440809
		TBC	640..857	CDD:214540	59/267 (22%)