Protein Alignment Tbc1d22 and Tbc1d22a

DIOPT Version :10

• Sequence 1: NP_650941.3
• Gene: Tbc1d22 / 42498
• FlyBaseID: FBgn0038855
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: XP_038936251.1
• Gene: Tbc1d22a / 689443
• RGDID: 1306588
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 237/543 - (43%)
• Similarity: 313/543 - (57%)
• Gaps: 84/543 - (15%)

  Fly    52 FWKNSGRRVPG----------------------RPSPKRELEKAAAVGVAVGRGAAPGSGMVSTF 94
            |||.|..:|||                      :.:|     |.....|...|        ||||
  Rat    10 FWKRSNSKVPGSIQHVYGAQHPPFDPLLHGTLLKSTP-----KVPTTPVKAKR--------VSTF 61

  Fly    95 TEYQKSVSDAWDMG-DDEFCIISSTEAAAAAVGAGDAAHFSRQVSQTVALNVIETHS-RSNQNHN 157
            .|::.:.|||||.| ||:..:..:||:            .:.:|....|..|:..|| |.||...
  Rat    62 QEFESNTSDAWDAGEDDDELLAMATES------------LNSEVVMETAHRVLRNHSQRQNQPSQ 114

  Fly   158 AS----------------------RSANESGADLVPVSSSSTDDCKEDRR--SLPDSNENRSRLR 198
            ..                      :|.:||.   .|..|.||.|....:|  |||     .|...
  Rat   115 KKPEPEPQPIAEPPVAPSGDLRLVKSVSESH---TPCPSESTSDTVPLQRSQSLP-----HSATV 171

  Fly   199 NYPGRPQLQKISSNCQDSEYETKIEKFQVVLDSPQLDLVALKKISWSGVPRKMRAVSWRLLSKYL 263
            ...|......:..:.......::::||:.:|..|..||..|:|:||||:|:.:|.::|:|||.||
  Rat   172 TLSGTSDTHALGGSALSKRETSRLDKFKQLLAGPNTDLEELRKLSWSGIPKPVRPMTWKLLSGYL 236

  Fly   264 PPSSERRMAVLESKRQGYQDLRHNYFRVDSQDETQQDTYRQIHIDVPRMNPQIPLFQQQLVQEMF 328
            |.:.:||.|.|:.|::.|.....:|:. ...||..||||||||||:|||:|: .|..|..|.|:|
  Rat   237 PANVDRRPATLQRKQKEYFAFIEHYYN-SRNDEVHQDTYRQIHIDIPRMSPE-ALILQPKVTEIF 299

  Fly   329 ERILFIWAIRHPASGYVQGINDLVTPFFIVFLQEALTPNTDLEKYDMSTLPEETRNIIEADSFWC 393
            ||||||||||||||||||||||||||||:||:.| .|...|::|.|:|::|.|....||||::||
  Rat   300 ERILFIWAIRHPASGYVQGINDLVTPFFVVFICE-YTDQEDVDKVDVSSVPAEVLRNIEADTYWC 363

  Fly   394 LSKFLDCIQDNYIFAQLGIQEKVNQLKDLIQRIDVNLHRHLQAHGVDYLQFSFRWMNNLLTRELP 458
            :||.||.|||||.|||.|||.||..|::|:.|||..:||||..|.|.||||:||||||||.||||
  Rat   364 MSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDERVHRHLDGHEVRYLQFAFRWMNNLLMRELP 428

  Fly   459 LHCTIRLWDTYLAESDGFALFHLYVCAAFLLHWKEQLMQQNDFQGLMLLLQNLPTHNWSDRQINV 523
            |.|||||||||.:|.:||:.||||||||||:.|:.:::::.|||.|:|.||||||..|.|:.:::
  Rat   429 LRCTIRLWDTYQSEPEGFSHFHLYVCAAFLVRWRREILEERDFQELLLFLQNLPTARWDDQDVSL 493

  Fly   524 LLAEAFRLKFTYADAPKHLETKS 546
            |||||:||||.:||||.|.:..|
  Rat   494 LLAEAYRLKFAFADAPNHYKKSS 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d22	NP_650941.3	TBC	243..496	CDD:214540	153/252 (61%)
Tbc1d22a	XP_038936251.1	TBC	216..466	CDD:214540	153/252 (61%)