Protein Alignment Tbc1d22 and tbc1d10ab

DIOPT Version :10

• Sequence 1: NP_650941.3
• Gene: Tbc1d22 / 42498
• FlyBaseID: FBgn0038855
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: XP_073770520.1
• Gene: tbc1d10ab / 562628
• ZFINID: ZDB-GENE-081105-145
• Length: 479
• Species: Danio rerio
• Alignment Length: 378
• Identity: 84/378 - (22%)
• Similarity: 137/378 - (36%)
• Gaps: 86/378 - (22%)

  Fly   207 QKISSNCQDSEY------ETKIEKFQVVLDSPQL----------DLVALKKISW--------SGV 247
            |:.||...|||.      |.:.:|:..:..:.|.          |::..::..|        ..:
Zfish    28 QESSSRGSDSELNGFANTEVQPDKYGFIGGAQQTAGENSDDIPPDVLRQREAKWLDMLNNWDKWM 92

  Fly   248 PRKMRAVSWRLLSKYLPPSSERRMAVLESKRQGYQDLRHNYFR-VDSQ-------DETQQDTYRQ 304
            .:|.:.|..| ..|.:|||...|..:..|..:..::.....|: :|||       |..::|.:||
Zfish    93 AKKHKKVKLR-CQKGIPPSLRGRAWLYLSGGKVKKEQNPGKFKELDSQPGDPKWLDVIEKDLHRQ 156

  Fly   305 IHIDVPRMNPQIPLFQQQLV-------QEMFERILFIWAIRHPASGYVQGINDLVTPFFIVFLQE 362
            ..            |.:..|       |::| |:|..:.:..|..||.|.    ..|...|.|..
Zfish   157 FP------------FHEMFVARGGHGQQDLF-RVLKAYTLHRPEEGYCQA----QAPIAAVLLMH 204

  Fly   363 ALTPNTDLEKYDMSTLPEETRNIIEADSFWCLSKFLDCIQDNYIFAQL-GIQEKVNQLKDLIQRI 426
                           :|.|       |:||.|.:..:.....|..|.| .||.....|..|::|:
Zfish   205 ---------------MPAE-------DAFWGLVQICEKYLPGYYSAGLEAIQLDGEILFALLKRV 247

  Fly   427 DVNLHRHLQAHGVDYLQFSFRWMNNLLTRELPLHCTIRLWDTYLAESDGFALFHLYVCAAFLLHW 491
            ....||||:.:.:|.:.:...|.....:|.||....:|:||.:..|..........|....:|..
Zfish   248 SPVAHRHLKKYKIDPILYMTEWFMCAFSRTLPWASVLRVWDMFFCEGVKIIFRVGLVLLKCMLGS 312

  Fly   492 KEQLMQ-QNDFQGLMLLLQNLPTHNWSDRQINVLLAEAFRLKFTYADAPK-HL 542
            .|:|.. |..::.:.||....|.:    .|...|:.|...|..:..|..| ||
Zfish   313 PEKLKACQGQYETMELLRSIEPRY----MQEAFLVQEVIDLPVSERDIEKEHL 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d22	NP_650941.3	TBC	243..496	CDD:214540	61/276 (22%)
tbc1d10ab	XP_073770520.1	None