Protein Alignment Tbc1d22 and TBC1D16

DIOPT Version :10

• Sequence 1: NP_650941.3
• Gene: Tbc1d22 / 42498
• FlyBaseID: FBgn0038855
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: NP_609403.2
• Gene: TBC1D16 / 34431
• FlyBaseID: FBgn0032249
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 132/565 - (23%)
• Similarity: 218/565 - (38%)
• Gaps: 147/565 - (26%)

  Fly    19 ESTAAATGTAGAGVAVVTVASGAGPTPGANSSTFWKNSGRRVPGRPSPKRELEKAAAVGVAVGRG 83
            :|...:..|.|:||       |.||   |..:..|     ..|...:.|..||
  Fly   201 DSNNCSDCTNGSGV-------GDGP---ATDNPKW-----TTPELLAFKHNLE------------ 238

  Fly    84 AAPGSGMVSTFTEYQKSVSDAWDMGDDEFCIISSTEAAAAAVGAGDAAHFSRQVSQTVALNVI-- 146
             .|.||. ||..:.|||                          |....|||..:||..:|.:.
  Fly   239 -FPDSGN-STPADRQKS--------------------------AMKCRHFSVDLSQMRSLRLFFN 275

  Fly   147 ETHSRSNQNHNASRSA-------NESGAD-LVPV-------SSSSTDDCKEDRRSLP-------D 189
            :.:..|.|...|||.:       :..|.| |..|       ..:.|.:..:|:..||       .
  Fly   276 DDNCTSGQLVIASRESQYKILHFHYGGLDHLAQVLHQWHCFLHNITSETGQDKFDLPYRHFMVCR 340

  Fly   190 SNENRSRLRNYPGRPQLQKISSNCQDSEYETKI-EKFQVVLDSPQLDLVALKKISWSGVPRKMRA 253
            ....:|.:  :|....::||::|   ..|.|.: ||.|:     :.||:..|.:.:.|:.:.:|.
  Fly   341 PEVKKSEM--HPDEGDVKKITTN---FFYGTLLNEKGQI-----EDDLLLRKCVFFGGLEKSLRK 395

  Fly   254 VSWRLLSKYLPPSS--ERRMAVLESKRQGYQDLRHNYFRVDSQDETQQ-DTYRQIHI----DVPR 311
            ..|..|.|....||  |.|..:::.|||.|:::...  |:.|....|| ..::.:.|    ||.|
  Fly   396 TVWPFLLKCYSFSSTFEDRAVLMDIKRQEYEEITRK--RLYSMSPEQQIHFWKTVQIVVEKDVVR 458

  Fly   312 MNPQIPLF--QQQLVQEMFERILFIWAIRHPASGYVQGINDLVTPFFIVFLQEALTPNTDLEKYD 374
            .:...|.|  ......|:.:.||..:|:.:....|.||::||:.|...
  Fly   459 TDRTNPFFCGDDNPNTEVMKNILLNFAVYNTGMSYSQGMSDLLAPVLC----------------- 506

  Fly   375 MSTLPEETRNIIEADSFWCLSKFLDCIQDNYIF---AQLGIQEKVNQLKDLIQRIDVNLHRHLQA 436
                  |.:|  |:::|||   |:..:|..:..   ....:...::.|::||:.:..:.::||:.
  Fly   507 ------EVQN--ESETFWC---FVGLMQRAFFVCTPTDRDVDHNLSYLRELIRIMLPHFYKHLEQ 560

  Fly   437 HGVDY-LQFSFRWMNNLLTRELPLHCTIRLWD----TYLAESDGFALFHLYVCAAFLLHWKEQLM 496
            |.... |.|..||:.....||......||:|:    .||.:     .|||::|.|.:..:.:.::
  Fly   561 HNDSMELLFCHRWLLLCFKREFTEAVVIRMWEACWSNYLTD-----YFHLFLCLAIIAVYADDVV 620

  Fly   497 QQNDFQGLMLL-LQNLPTHNWSDRQINVLLAEAFRLKFTYADAPK 540
            .||.....||| ..:|..  :.|.|:  :|.:|..|...|...||
  Fly   621 AQNLRPDEMLLHFSSLAM--YMDGQL--ILRKARGLLHQYRQLPK 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d22	NP_650941.3	TBC	243..496	CDD:214540	63/269 (23%)
TBC1D16	NP_609403.2	TBC	387..618	CDD:214540	63/265 (24%)