DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5745 and Tbc1d15-17

DIOPT Version :9

Sequence 1:	NP_650941.3	Gene:	CG5745 / 42498	FlyBaseID:	FBgn0038855	Length:	546	Species:	Drosophila melanogaster
Sequence 2:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	98/417 - (23%)
Similarity:	166/417 - (39%)	Gaps:	108/417 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 AGDAAHFSRQVS----QTVALNVIETHSRSNQNHNASRSANESGADLVPVSSSSTDDCKEDR--R 185
            :||     ||.|    |.:.|:.....:.|:...:...||.:|.||    |...|.:.::::  .
  Fly   274 SGD-----RQTSPDNYQIIGLSGSTNSACSSNGQSRGGSAEKSPAD----SELETLNAQDEKIVN 329

  Fly   186 SLPDSNENRSRLRNYPGRPQLQKISSNCQDSEYETKIEKFQVVLDSPQLDLVALKKISW-SGVPR 249
            :|||    |.|:..  |.|..            ||:..:||.. |....|...:|::.: .||.:
  Fly   330 NLPD----RQRVER--GHPLT------------ETQWLEFQTP-DGRISDSARIKELIFRGGVVQ 375

  Fly   250 KMRAVSWR-LLSKYLPPSSERRMAVLESKRQ---GYQDLRHNYFRVDSQDETQQDTYR----QIH 306
            .:|...|: ||:.||  .|:..:..:|.::|   .|.:::..:..:.:..|.....||    ||.
  Fly   376 SLRPEVWKFLLNYYL--WSDTHVERIERRKQKSIEYYNMKAQWLAMTTTQEANFCGYRERKCQIE 438

  Fly   307 IDVPRM-----------NPQIPLFQQQLVQEMFERILFIWAIRHPASGYVQGINDLVTPFFIVFL 360
            .||.|.           ||.:.|.|         .||..:.:.:...|||||::||:.|...:
  Fly   439 KDVKRTDRSLQFFAGEDNPNLTLLQ---------GILMTYVMYNFDLGYVQGMSDLLAPILEI-- 492

  Fly   361 QEALTPNTDLEKYDMSTLPEETRNIIEADSFWCLSKFLDCIQDNYIFAQLGIQEKVNQLKDLIQR 425
                                   .:.|.|:|||...|::.:..|:...|.|::.:..|::.||:.
  Fly   493 -----------------------QVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEF 534

  Fly   426 IDVNLHRHLQAHGVDYLQFSFRWMNNLLTRELPLHCTIRLWD---TYLAESDGFALFHLYVCAAF 487
            .:..|..::::|..|.:.|.|||:.....|||.....::||:   |.|...:    |||....|.
  Fly   535 ANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPN----FHLLFSVAI 595

  Fly   488 L-----------LHWKEQLMQQNDFQG 503
            |           ..:.|.|...|:..|
  Fly   596 LDQETRVIIDSQYEFTEILKHVNELSG 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5745	NP_650941.3	TBC	243..496	CDD:214540	66/286 (23%)
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	65/268 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456570
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940