Protein Alignment CG5745 and tbc1d22b

DIOPT Version :9

• Sequence 1: NP_650941.3
• Gene: CG5745 / 42498
• FlyBaseID: FBgn0038855
• Length: 546
• Species: Drosophila melanogaster
• Sequence 2: XP_002936267.1
• Gene: tbc1d22b / 100380202
• XenbaseID: XB-GENE-961200
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 525
• Identity: 246/525 - (46%)
• Similarity: 331/525 - (63%)
• Gaps: 59/525 - (11%)

  Fly    48 NSSTFWKNSGRRVPG---------RPSPKRELEKAAAVGVAVGRGAAPGSGMVSTFTEYQKSVSD 103
            |:..|||.| .::||         .|.....|.|:.....:..:.....|...|:|.|:.::.||
 Frog     4 NNRQFWKRS-TKLPGSIQPVYGAQHPPLDPRLNKSYISDRSRRQPLHLKSRKASSFHEFARNTSD 67

  Fly   104 AWDMGDDEFCIISSTEAAAAAVGAGDAAHFS------RQVSQTVALNVIETHSRSNQNH----NA 158
            |||:.||        :.|....|.||..:.|      .:|::..|..|||:|.:..:..    :.
 Frog    68 AWDIEDD--------DDADDDDGGGDVLYASPYQTLNSRVAEVTAAQVIESHLKLREESPCQPSV 124

  Fly   159 SRSANESGADLVPVSSSSTDDCKEDR-----RSLPDSNENRSRLRNYPGRPQLQKIS-SNCQDS- 216
            ::|.:|.....|     :.||..:.:     :|||        ||  |..|.:.:|| .|...:
 Frog   125 TKSVSEDHLHRV-----TADDLPQKKYLHKQQSLP--------LR--PIIPLVARISDQNASGAP 174

  Fly   217 ----EYETKIEKFQVVLDSPQLDLVALKKISWSGVPRKMRAVSWRLLSKYLPPSSERRMAVLESK 277
                ..:|::|||:.:|..|..||..|:|.||.||||::|..:|||||.|||.:.||||..|:.|
 Frog   175 PMTVREKTRLEKFRQLLSCPNTDLDELRKCSWPGVPREVRPTTWRLLSGYLPANKERRMLTLQRK 239

  Fly   278 RQGYQDLRHNYFRVDSQ-DETQQDTYRQIHIDVPRMNPQIPLFQQQLVQEMFERILFIWAIRHPA 341
            |:.|......|:  ||: :|..||||||||||:||.||.||||||.:|||:||||||||||||||
 Frog   240 REEYFGFIEQYY--DSRNEEHHQDTYRQIHIDIPRTNPLIPLFQQAIVQEIFERILFIWAIRHPA 302

  Fly   342 SGYVQGINDLVTPFFIVFLQEALTPNTDLEKYDMSTLPEETRNIIEADSFWCLSKFLDCIQDNYI 406
            |||||||||||||||:|||.|.:  ..|:|.:|:::|.:||...|||||||.:||.||.|||||.
 Frog   303 SGYVQGINDLVTPFFVVFLTEHV--EEDVENFDVASLCQETLRNIEADSFWSMSKLLDGIQDNYT 365

  Fly   407 FAQLGIQEKVNQLKDLIQRIDVNLHRHLQAHGVDYLQFSFRWMNNLLTRELPLHCTIRLWDTYLA 471
            |||.|||:||..|::|:.|||..:|.|.:.:.|:||||:||||||||.|||||.|||||||||.|
 Frog   366 FAQPGIQKKVKALEELVSRIDEQVHNHFRKYEVEYLQFAFRWMNNLLMRELPLRCTIRLWDTYQA 430

  Fly   472 ESDGFALFHLYVCAAFLLHWKEQLMQQNDFQGLMLLLQNLPTHNWSDRQINVLLAEAFRLKFTYA 536
            |.:||:.||||||||||:.|:::::::.|||||::|||||||.:|.:.:|.:|||||:|||:.:|
 Frog   431 EPEGFSHFHLYVCAAFLIKWRKEILEETDFQGLLMLLQNLPTIHWGNEEIGLLLAEAYRLKYMFA 495

  Fly   537 DAPKH 541
            |||.|
 Frog   496 DAPNH 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5745	NP_650941.3	TBC	243..496	CDD:214540	162/253 (64%)
tbc1d22b	XP_002936267.1	TBC	205..455	CDD:214540	162/253 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	322	1.000	Domainoid score	I1219
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H23043
Inparanoid	1	1.050	435	1.000	Inparanoid score	I1650
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D220411at33208
OrthoFinder	1	1.000	-	-		FOG0002429
OrthoInspector	1	1.000	-	-		otm48602
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1614
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160