Protein Alignment CG7044 and brat1

DIOPT Version :10

• Sequence 1: NP_650940.2
• Gene: CG7044 / 42497
• FlyBaseID: FBgn0038854
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: XP_021331514.1
• Gene: brat1 / 678547
• ZFINID: ZDB-GENE-060421-6989
• Length: 823
• Species: Danio rerio
• Alignment Length: 1022
• Identity: 213/1022 - (20%)
• Similarity: 367/1022 - (35%)
• Gaps: 307/1022 - (30%)

  Fly    32 EKLL-----THLQAKENAFVLQAPFVVEWVDR-CITAVTEDFKKIHPKVISFMLNLTSFLANNEW 90
            ||||     .|.|:.....:...|.::|::.. |.:..|:      |.::||.|.||..||.::.
Zfish    30 EKLLDWFKDLHSQSNGQVLLEHQPCLLEFISSVCASKATD------PAILSFTLKLTGLLAASKQ 88

  Fly    91 MIVRLRELDIVNRAVKLLQREH----NL--SPSIKLGGIRLMKAITVYSMGLAFLRMHRIWTLLI 149
            ....|.|   ....|.:.:||.    :|  ..|::.|.|:.:..:..:...|.|:....:..:::
Zfish    89 DFHLLEE---GGHLVCVFEREAWSVCDLWEDASVRSGWIQGLLNMLKHQQALDFICRQGLIKVIL 150

  Fly   150 QYSNNDHTLYVVREARQVLYNMV-----------------YKSCDKLHDKAVTLEILSEIMQPIH 197
            |. .||.:|:|...|.|:|..::                 .||...|...:|:.||.:.:::.:
Zfish   151 QL-QNDRSLFVACLANQLLVQILKLLTPSDVTSGSDAVVSSKSSSSLDWVSVSSEITNAVVEAL- 213

  Fly   198 DNLYKNTDGVERIHVKVDDNEMLHKISSTLDLLSYILQQTLVLEE--RTTLIILLKEHHDFEITV 260
                              .:|...::...:.|||.:|.|   .||  |::|
Zfish   214 ------------------SSENHPQVLQGVQLLSLVLSQ---CEEPIRSSL-------------- 243

  Fly   261 WK--------LIDMTHNPYFTEKIFTTLSSYNFALLLHEKLLNPNATEPSEEFTEFGLAFFNLMK 317
            ||        ||:....| .|:.:.|.|.:.....||.:      :....|||.|..|...|
Zfish   244 WKDVLPPLEVLINRGSEP-LTQPLMTVLRAAVMTPLLGQ------SEYKVEEFLEVMLGTGN--- 298

  Fly   318 FLITRKDGL----SFVKLAELNHVLWKKLGPRAPKEIVIQQERVTFENQLICFHMLPLLFSMKYA 378
                ||:|:    ..|||.:...||.:|    |...|::..:.|:.::|
Zfish   299 ----RKEGILCATLIVKLEKCPKVLKRK----AMDIILLPLQCVSTQSQ---------------- 339

  Fly   379 QKIADEESKIELF-------DAYVVKLLEISCEQTLRLCYTMRDNFFSADGMAVGLVTAGLANKC 436
                |.|.:::|.       .|..:.||..|......|.:   ..:|  :|:.:..||:.:.
Zfish   340 ----DAEKEVDLVLKEPLSQKALCISLLVQSLSSLAELAH---KEYF--EGVCIPSVTSRVV--- 392

  Fly   437 IHSLLALENVLDREQAVTVC-----QALLYVLREAVAMSVITNNGEDDCHSVSSAGSSYLKLYPR 496
                          |.:.||     .:||:|       |..|       |.:.|.......|...
Zfish   393 --------------QLLRVCSGHCTSSLLHV-------SACT-------HLIGSCKIQRCGLDTL 429

  Fly   497 GTEQVVNDPQVLHSVMVGLRTLIERFKITWKESVETIGLVNCLAFVLENTSMDARCTVQALKLVQ 561
            |...|..|...|...:.|:  |::..|                       |.|:..||  ||...
Zfish   430 GALSVYEDNLDLRKDIFGV--LLDYLK-----------------------SPDSHATV--LKKTF 467

  Fly   562 LAVEHFLS-----PNMALLVDNLQGSALVCLGPIIVKRMHDTMWEVRDTTLELTTSIASISRIKF 621
            .||..::.     |::...:.|       .|.|::.|||.|..|||||:|||..|.: :::....
Zfish   468 QAVLRWIGVCASFPDLLQFISN-------DLFPVLEKRMCDVRWEVRDSTLEFITQL-TVALSDN 524

  Fly   622 PAFQRFLIDSKIPPIVYEMAKNDSEVYVRASAFQCLSQMVS-----------INLLWENGLSQLD 675
            ..|...|..|.:..|:..:. :|:|.||||||...:.:.|:           |||| |..|:|
Zfish   525 SGFVEVLYTSGLVSILLSLL-SDTEGYVRASAVTAVGEAVTSSVQQMALVSKINLL-EEALAQ-- 585

  Fly   676 LVDHLLFVMYRETNDIVRSEAVITLMKIYEHRKIHEKYKNTLFSTLNYCVIG--DHHTEVKLNAL 738
                ::.::.::|....|...|.|.....:.........::|.|.|:   :|  |...|||::.|
Zfish   586 ----MMIILSQDTEGFPRRAVVKTFTSWLKGSNPITALDSSLSSVLS---LGGNDFDWEVKMHTL 643

  Fly   739 NFWRREFYRQFSNQGMIDGSFPTVTFSKEQKKIVTLTEKEIQTSIAKVFGEVQQYGYFGILLKCL 803
                 |.......:.:....:...:||..::           |.:.:...:::..|.|.:||..|
Zfish   644 -----ELAEALMEKMLTCCPYAVQSFSSSER-----------TRLTQSLSKLKDLGLFDVLLNGL 692

  Fly   804 RE------ETSMEVLEFLIKGVKTMTEKFERYKGIMEEIEMRSPLSDRERPRFDFPSQPQPTPIP 862
            .:      |.|.::| ..:|.:......|:....:::....|
Zfish   693 FDCDRPVCEKSCQLL-LKLKRLNAEKADFDHDALVLKACGNR----------------------- 733

  Fly   863 QQPPVNPTEADEVIESILNSQDAQLLEKAFETQMQINAQGKTAEKRHIDEFYYKQFAVPLRQFFE 927
                    ..|||....||.|..    ||.|..:....:|...:...|.|       :||....:
Zfish   734 --------WGDEVQSRFLNKQQV----KASEHVLIGGGEGTEKDLHCIKE-------IPLSVILQ 779

  Fly   928 ELKTIDLDQLVKQHQEWFECKENFTSLLDDILGALKRDDENMISDCY 974
            .|...|:.:::|...:  ....:..||::|||.|.::.:||:: |||
Zfish   780 ILDLDDMQRMLKLSSD--HVVNSPRSLMEDILSAAQQSEENIV-DCY 823

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7044	NP_650940.2	HEAT repeat	571..620	CDD:293787	16/48 (33%)
		HEAT repeat	632..663	CDD:293787	10/41 (24%)
		HEAT repeat	672..702	CDD:293787	5/29 (17%)
		HEAT repeat	714..740	CDD:293787	9/27 (33%)
brat1	XP_021331514.1	None