DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP93B and ROPGAP3

DIOPT Version :9

Sequence 1:	NP_650939.2	Gene:	RhoGAP93B / 42496	FlyBaseID:	FBgn0038853	Length:	1330	Species:	Drosophila melanogaster
Sequence 2:	NP_850458.1	Gene:	ROPGAP3 / 819283	AraportID:	AT2G46710	Length:	455	Species:	Arabidopsis thaliana

Alignment Length:	259	Identity:	71/259 - (27%)
Similarity:	113/259 - (43%)	Gaps:	40/259 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1076 TCFMEVSK----------WPIHVQ-ISHYATVCCRRLDRI-GSSGRRMAKKPTVDEVEQARQQIL 1128
            :|.||..:          ||..|: :||..      .||. |..|.....:|.|    ..|....
plant    89 SCAMERGEDDVVASMDIGWPTEVKHVSHVT------FDRFNGFLGLPSELEPEV----PPRAPSA 143

  Fly  1129 RNSMFGNTLSEVMDLQKEKFPFRKLPWIQTTLSEHVLLLNGKQTEGIFRVSADVDEVGCMKNRLD 1193
            ..|:||.:...:.....::  ...:|.|...:.:.:....|.:.|||||::.|..:...::.:|:
plant   144 SVSVFGVSAKSMQCSYDDR--GNSVPTILLRMQKRLYTEGGLKAEGIFRINPDNGKEEHVRRQLN 206

  Fly  1194 RWDVPDYKNTLVDAHTPASLLKLWYREL----YDPLIPDAYYEDCVNTEDPDKAKEIVNKLPEIN 1254
            ...||    ..:|.|..|.|:|.|:|||    .|.|.|:.... | |||  :....:|..||.:.
plant   207 CGVVP----RGIDVHCLAGLIKAWFRELPTGVLDVLTPEQVMR-C-NTE--EDCSRLVILLPPVE 263

  Fly  1255 QLVLTYLIHFLQQFAIPEVVSCTKMDSSNLAMVFAPNCLRCTSEDPKVILENARKEMSFMRTLI 1318
            ..:|.:.|..:..  :.|.....||::.|:|||||||..:..  ||...|.:|.:.|:|::|||
plant   264 SAILDWAIGLMAD--VVEHEQFNKMNARNVAMVFAPNMTQMA--DPLTALIHAVQVMNFLKTLI 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP93B	NP_650939.2	WW	50..75	CDD:278809
		MyTH4	956..1122	CDD:295320	14/57 (25%)
		RhoGAP_KIAA1688	1133..1320	CDD:239854	55/190 (29%)
ROPGAP3	NP_850458.1	CRIB	103..143	CDD:238077	12/49 (24%)
ROPGAP3	NP_850458.1	RhoGAP	167..323	CDD:238090	51/167 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	75	1.000	Domainoid score	I3184
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2562
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910