DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP93B and Arhgap24

DIOPT Version :9

Sequence 1:	NP_650939.2	Gene:	RhoGAP93B / 42496	FlyBaseID:	FBgn0038853	Length:	1330	Species:	Drosophila melanogaster
Sequence 2:	XP_038947750.1	Gene:	Arhgap24 / 305156	RGDID:	1306669	Length:	815	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	69/218 - (31%)
Similarity:	105/218 - (48%)	Gaps:	19/218 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly  1118 DEVEQARQQI---LRNSMFGNTLSEVMDLQKEKFPFRKLPWIQTTLSEHVLLLNGKQTEGIFRVS 1179
            |.|:..|:.|   ....:||..|.:.:..:| ::..|..|.:.....:.: ...|.:.||:||:.
  Rat   181 DWVKSIRRVIWGPFGGGIFGQKLEDTVRYEK-RYGNRLAPMLVEQCVDFI-RQRGLKEEGLFRLP 243

  Fly  1180 ADVDEVGCMKNRLDRWDVPDY-KNTLVDAHTPASLLKLWYRELYDPLIPDAYYED---C---VNT 1237
            ...:.|..:::..|..:.|.: .||  |.||.||||||:.|||.:|::|.|.|||   |   ::.
  Rat   244 GQANLVKELQDAFDCGEKPSFDSNT--DVHTVASLLKLYLRELPEPVVPYAKYEDFLSCATLLSK 306

  Fly  1238 EDPDKAKEI---VNKLPEINQLVLTYLIHFLQQFAIPEVVSCTKMDSSNLAMVFAPNCLRCTSED 1299
            |:....||:   |..||.:|..:|.|:..||.:  :.......||.:.|||.||.||.||...||
  Rat   307 EEEAGVKELTKQVKSLPVVNYNLLKYICRFLDE--VQSYSGVNKMSAQNLATVFGPNILRPKVED 369

  Fly  1300 PKVILENARKEMSFMRTLIQHMD 1322
            |..|:|........|..:|...|
  Rat   370 PLTIMEGTVVVQQLMSVMISKHD 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP93B	NP_650939.2	WW	50..75	CDD:278809
		MyTH4	956..1122	CDD:295320	2/3 (67%)
		RhoGAP_KIAA1688	1133..1320	CDD:239854	64/196 (33%)
Arhgap24	XP_038947750.1	PH_RhoGap24	84..197	CDD:241530	4/15 (27%)
		RhoGAP_ARHGAP22_24_25	197..395	CDD:239855	65/202 (32%)
		Smc	<716..>802	CDD:224117
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910