Protein Alignment RhoGAP93B and rga7

DIOPT Version :10

• Sequence 1: NP_650939.2
• Gene: RhoGAP93B / 42496
• FlyBaseID: FBgn0038853
• Length: 1330
• Species: Drosophila melanogaster
• Sequence 2: NP_595866.1
• Gene: rga7 / 2540635
• PomBaseID: SPBC23G7.08C
• Length: 695
• Species: Schizosaccharomyces pombe
• Alignment Length: 944
• Identity: 176/944 - (18%)
• Similarity: 294/944 - (31%)
• Gaps: 358/944 - (37%)

  Fly   464 SSDSSPQSPIS--PQTKSS------RQAKTSA--TSTVPQLQHSPRLQEPSHSLDLLSLERISLG 518
            ||.::|.||.:  |.|.||      ::.|..|  .|.:.....:.|:::     .||:.:.::
pombe     6 SSSTTPASPPTSPPNTTSSDDFAVLKEPKVEAILNSELGLAILNDRIKD-----YLLTCKELA-- 63

  Fly   519 KSGPISPGGGTENLGLLTHSSRGSNDSARQRQKSNNSSANRSQSHHYPGQS-------------- 569
                          |.....|....:|.:..||...|.....||.|:..||
pombe    64 --------------GFFKKRSILEEESGKNLQKLAKSYLETFQSKHHSPQSFSASVITSMEIHEQ 114

  Fly   570 ------SLRHSASSSLDK-RGYHVGGGSGDGRGVTGGEKRRSKQHHYQQQADNSDVEYDNGNTSP 627
                  :|:.:.|:..|: ..:|           ...|::|.....|.::.:|:.:|
pombe   115 LANHSLTLQKTLSAFSDQVIEFH-----------KNAERKRKSIKEYAKKQENAYLE-------- 160

  Fly   628 LYTNWDQEMPHLLPLKHYIIEQAKLSGRYEYRGGDGGDSDSYHSDSQSEHSLSGHEPDNEDSDGG 692
                             .:::..|...|::                                  |
pombe   161 -----------------AVMQMDKSKSRFK----------------------------------G 174

  Fly   693 SDTHGGYLEHNYGMIDDYANMGDSVSYYAYMYPP--------HDPAGREDISENVEAVLEGIGGN 749
            ::|     |:|..:  |..|.|||.....:..|.        .|.|..:  :||.|:.:.....|
pombe   175 AET-----EYNRAL--DNKNTGDSQKKVGFFKPKSNAQLTKLEDEARLK--AENAESDMHSKIEN 230

  Fly   750 ATEPSAPTATAPKPKPRYQ-ISYYDTVSHSPSAGSGYHGQQLYSN-------------TPPYSGH 800
            |...........:|....| .|....:..|..|....:.:...||             ||...|.
pombe   231 AQNVQKQLLCIHRPNYIKQFFSLQREIESSLIANYLRYTKLCESNTLLNGLTIRPQKPTPTNCGL 295

  Fly   801 GHG-----------HHVPPPSLPHQQQLHLEPSDTKQKQSQTLPSPNRQISRLAGAGHQGSGPAA 854
            .|.           .:|...|:.|:.  :..|:|..:.:....||            ..|:|.:|
pombe   296 QHALDNINANTDFVQYVLHASIKHED--NKNPTDASKTKIIQPPS------------SYGTGSSA 346

  Fly   855 SSKEETGHSTVAGQQQVTVGTVTPASLSRPGHKMAPPSLKPTIQQIFPPSERAPGMGNLGLGGPT 919
            .......:.|:    :||....:|...:.|.     ||..|.      ||..:|...|.....|:
pombe   347 GKTNPPVNPTI----KVTAAIPSPLQNTNPA-----PSTFPN------PSVASPAFPNSSTSNPS 396

  Fly   920 LACMKECDIEKFAADNLNLHSKGIFRKKASVRDMLSWTAEAISRPMLALSRDKADKKTAIELFKL 984
            .|......:    |..|         |.::..|....::.:.|.|           :|:..|..
pombe   397 TAPASASPL----ASTL---------KPSTANDTNGSSSSSSSNP-----------RTSSPLAS- 436

  Fly   985 VQIYMADRKARIGMTLNSVAIEIISASLPQQQLRDELYVQLCRQTTENPKRDSLIRGWELMAICL 1049
                .|:.|..:...    :..::..:||..|           .||....|:
pombe   437 ----NAENKPPVAQQ----SPPVLLPTLPPIQ-----------TTTIQTSRE------------- 469

  Fly  1050 SYVPPSPTFQPTLLNYVNRHRDPSFATCFMEVSKWPIHVQISHYATVCCRRLDRIGSSGRRMAKK 1114
             ..||     |:.:| .||...|...|   .||..|                           ..
pombe   470 -VAPP-----PSSIN-SNRAASPFRPT---SVSPQP---------------------------SS 497

  Fly  1115 PTVDEVEQARQQILRNSMFGNTLSEVMDLQKEKFPFRKLPWIQTTLSEHVLLLN----------- 1168
            ||            ::.:||..|..::                  |.||..:.|
pombe   498 PT------------KSLLFGARLDAII------------------LREHSNIPNIVMQCTSQVEN 532

  Fly  1169 -GKQTEGIFRVSADVDEVGCMK-----NRLDRWDVP-DYKNTLVDAHTPASLLKLWYRELYDPLI 1226
             |...:||:||.:....|..::     |.|.:...| ||:|   |.|..|.|||:::|||.:|||
pombe   533 FGLNLQGIYRVPSSSARVNMLRSQFENNPLLQLHTPEDYEN---DVHAVADLLKIFFRELREPLI 594

  Fly  1227 PDAYYEDCV---NTEDPDKAKEIV----NKLPEINQLVLTYL-IHFLQQFAIPEVVSCTKMDSSN 1283
            ||.:..|.:   |.||..:.::.|    |.||:.|...:.:| ||..:   |.|.....||.::|
pombe   595 PDNHQRDFIDAGNVEDESRRRDAVHRAINDLPDANYSTIRHLTIHLAK---IKENSDVNKMSTNN 656

  Fly  1284 LAMVFAPNCLRCTSEDPKVILENARKEMSFMRTL 1317
            ||:::.|..:: .:..|::        .||.||:
pombe   657 LAIIWGPTIIK-QATIPEI--------SSFSRTI 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP93B	NP_650939.2	PRP40	1..>75	CDD:227435
		PAT1	<737..>892	CDD:401645	31/179 (17%)
		MyTH4	1004..1122	CDD:459939	19/117 (16%)
		RhoGAP_KIAA1688	1133..1320	CDD:239854	58/211 (27%)
rga7	NP_595866.1	F-BAR_Rgd1	39..277	CDD:153336	50/337 (15%)
		Herpes_BLLF1	<321..>479	CDD:282904	41/250 (16%)
		RhoGAP_fRGD1	504..692	CDD:239863	58/211 (27%)