Protein Alignment HHEX and YOX1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_013685.1
• Gene: YOX1 / 854981
• SGDID: S000004489
• Length: 385
• Species: Saccharomyces cerevisiae
• Alignment Length: 314
• Identity: 74/314 - (23%)
• Similarity: 115/314 - (36%)
• Gaps: 82/314 - (26%)

  Fly     7 SSKAAFSIENILEQKSSSHRSQSRRGSSQSPVAVTAGIATPHAL---------AMPKASLATGSS 62
            ||..:.|..|   .::|.|...  ||:.:.| .:...|..|.::         ::.:.|.|.|..
Yeast    22 SSPVSPSFTN---PRTSFHLDD--RGTIKLP-PLNTSINRPRSVESALRHTVTSLHENSSAYGDD 80

  Fly    63 SAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKN 127
            ....|.|.|:      ||.:..::|..:.....:.:|.|.:           |......:..:||
Yeast    81 MLKHTQSDSA------LSSQLNSSQETVDESHENLLLTPLN-----------SKKRDYSVSSKKN 128

  Fly   128 PSLFMPHFQAAAVAAAAAVQPTAYCDQYSPF---TMDCEGFP--NPASAAAALYCNAYPAASFYM 187
            ..|      ....||.:.:.|:|..::...|   |...|.||  .|....|.|
Yeast   129 DIL------TPLSAAKSIIIPSASKEKRRAFAFITHSQETFPKKEPKIDNAPL------------ 175

  Fly   188 SNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRR--AKWR 250
                .:||  :.|.:||:...|:|.|......|.|:|..||....:|::.|:.||||:|  .|.:
Yeast   176 ----ARRK--RRRTSSQELSILQAEFEKCPAPSKEKRIELAESCHMTEKAVQIWFQNKRQAVKRQ 234

  Fly   251 RANLSKRSASAQ-------------GPIAGAAV------GSPSSASSSSVPVLN 285
            |...||.:...|             .|:|....      ||..|.||||.|:.|
Yeast   235 RIATSKSTTIIQTVSPPSPPLDVHATPLASRVKADILRDGSSCSRSSSSSPLEN 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	19/52 (37%)
YOX1	NP_013685.1	COG5576	126..267	CDD:227863	42/164 (26%)