Protein Alignment HHEX and nkx2.1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_571851.1
• Gene: nkx2.1 / 81883
• ZFINID: ZDB-GENE-010404-1
• Length: 346
• Species: Danio rerio
• Alignment Length: 294
• Identity: 74/294 - (25%)
• Similarity: 106/294 - (36%)
• Gaps: 61/294 - (20%)

  Fly    12 FSIENILEQKSSSHRSQSRRGSS-QSPVA------VTAGIATPHALAMPKASLATGSSSAAPTPS 69
            ||:.:||.....|::..|..|:: .:|:|      ||......|.:         |.:...|...
Zfish    11 FSVSDILSPLEESYKKVSMEGNNLGAPLASYRQPQVTQAAMQQHHM---------GHNGTVPAAY 66

  Fly    70 PSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPD------PASLFYQQVLQLQKNP 128
            ..:|..:..||..|... |...::.:.:.|        |.|.|      .|:.:|      ..||
Zfish    67 HMTAAGVSQLSHTAMGG-YCNGNLGNMSDL--------PAYQDGMRGSTTATSWY------GTNP 116

  Fly   129 SLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFGVK 193
            .   |.|...          :.:....|...|   |..:..|:.|.:.....|..|       ..
Zfish   117 D---PRFSTI----------SRFMGSSSGMNM---GSMSTLSSLADVGKGMGPLTS-------TP 158

  Fly   194 RKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKRS 258
            |:..::.|:..|...||.||...||||..||.|||..:.||..|||.||||.|.|.:|....|.|
Zfish   159 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKVS 223

  Fly   259 ASAQGPIAGAAVGSPSSASSSSVPVLNLGSGSRC 292
            ........|:......|....:|||| :..|..|
Zfish   224 QQQMQQDNGSCQQQQQSPRRVAVPVL-VKDGKPC 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	26/50 (52%)
nkx2.1	NP_571851.1	Homeodomain	160..216	CDD:459649	26/55 (47%)