Protein Alignment HHEX and Nkx6-3

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_083278.1
• Gene: Nkx6-3 / 74561
• MGIID: 1921811
• Length: 262
• Species: Mus musculus
• Alignment Length: 265
• Identity: 73/265 - (27%)
• Similarity: 102/265 - (38%)
• Gaps: 46/265 - (17%)

  Fly    57 LATGSSSAAPTPSPSSATNIYDLS------REAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPAS 115
            ||..|...||....|...:.|.||      :.||...:.:..:.|..|..|.|...:. ||..|.
Mouse    16 LAQFSEMKAPMCQYSVQNSFYKLSPPGLGPQLAAGTPHGITDILSRPVATPNSSLLSG-YPHVAG 79

  Fly   116 LFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAY 180
            ..     .|......:.|  |..:.:.|....||...:.::....|..|...|        |:..
Mouse    80 FG-----GLSSQGVYYGP--QVGSFSKAGNEYPTRTRNCWADTGQDWRGSARP--------CSNT 129

  Fly   181 PAASFYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNR 245
            |..   :|:...|:|..:..||..|...||..|..:|||:..||..||..|.:|:.|||.|||||
Mouse   130 PDP---LSDTIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNR 191

  Fly   246 RAKWRRANLSKRSASAQGPIAGAAVGSPSSASSSSVPVLNLGSGSRCGQQSDEEDRMYLSEDDED 310
            |.|||:.:..:.|:|......||                   ||.|..  |:.||..|....|.|
Mouse   192 RTKWRKKSALEPSSSTPRAPGGA-------------------SGDRAA--SENEDDEYNKPLDPD 235

  Fly   311 DDEDE 315
            .|:::
Mouse   236 SDDEK 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	26/50 (52%)
Nkx6-3	NP_083278.1	Homeodomain	139..197	CDD:459649	28/57 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..237		13/60 (22%)