Protein Alignment HHEX and Vax1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_072158.1
• Gene: Vax1 / 64571
• RGDID: 621132
• Length: 336
• Species: Rattus norvegicus
• Alignment Length: 228
• Identity: 58/228 - (25%)
• Similarity: 87/228 - (38%)
• Gaps: 74/228 - (32%)

  Fly   120 QVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAA--AALYCNAYPA 182
            :..::.||     .|.::..:..|....|.|:..:           |..|.:|  |:..||...:
  Rat    17 EAARVSKN-----AHKESREIKGAEGSLPAAFLKE-----------PQGAFSASGASEDCNKSKS 65

  Fly   183 ASF----YMSNFGVKRKGGQIR-------------------FTSQQTKNLEARFASSKYLSPEER 224
            .|.    |.....|:...|.||                   ||::|...||..|...:|:...||
  Rat    66 NSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRER 130

  Fly   225 RHLALQLKLTDRQVKTWFQNRRAKWR---------RANLSKRSASA-------QG---------- 263
            ..||.||.|::.|||.||||||.|.:         |:.:|:.:|:.       ||
  Rat   131 TELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRLLEQGRLLSPPGLPA 195

  Fly   264 ---PIAGAAVGSPSSASSSSVPVLNLGSGSRCG 293
               |.|..|:|  |:....|:|.  ||:|:..|
  Rat   196 LLPPCATGALG--SALRGPSLPA--LGAGAAAG 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	25/78 (32%)
Vax1	NP_072158.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		4/26 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..69		6/18 (33%)
		vax upstream domain	72..99		5/26 (19%)
		homeobox	100..159		24/58 (41%)
		Homeodomain	101..157	CDD:459649	24/55 (44%)
		vax downstream domain	178..189		2/10 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..267
		vax terminal domain	315..323