Protein Alignment HHEX and nkx2.4a

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001104636.1
• Gene: nkx2.4a / 562300
• ZFINID: ZDB-GENE-030131-6336
• Length: 345
• Species: Danio rerio
• Alignment Length: 291
• Identity: 77/291 - (26%)
• Similarity: 108/291 - (37%)
• Gaps: 68/291 - (23%)

  Fly    36 SPVAVTAGIATPHALAMPKASLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMK--SMDSSAV 98
            :|.:|| .|.:|......|.|   |..|.....||..|      .|:...:|..|:  ||..:|.
Zfish     9 TPFSVT-DILSPIEETYKKFS---GMESTGNLTSPLGA------YRQPQVSQTGMQQHSMGHNAT 63

  Fly    99 LAPTSLRFNPIY--PDPASLFYQQVLQLQKNPSLF----MPHFQAAAVAAAAAVQPTAYCDQYSP 157
            :|.|       |  |...|.|....:....|.|:.    :|.:|.....:|||.
Zfish    64 VATT-------YHMPHSVSQFSHSAMGGYCNGSIANMGDLPSYQETMRNSAAAT----------- 110

  Fly   158 FTMDCEGF----PNPASAAAALYCNAYPAASFYMSNFG-----------------VKRKGGQIRF 201
                  |:    |:|..:..:.:..  |:....|:..|                 ..|:..::.|
Zfish   111 ------GWYGANPDPRYSTISRFMG--PSTGMNMTGMGTLTGMADTTKSIPPLHAAPRRKRRVLF 167

  Fly   202 TSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKRSASAQGPIA 266
            :..|...||.||...||||..||.|||..:.||..|||.||||.|.|.:|.  :|..|:.|....
Zfish   168 SQAQVCELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ--AKDKAAQQLQQE 230

  Fly   267 GAAVGSPSSASSSSVPVLNLGSGSRCGQQSD 297
            |.......|....:|||| :..|..|...|:
Zfish   231 GNLCQQQQSPRRVAVPVL-VKDGKPCQNGSN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	26/50 (52%)
nkx2.4a	NP_001104636.1	Homeodomain	161..217	CDD:459649	26/55 (47%)