Protein Alignment HHEX and BARX1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_067545.3
• Gene: BARX1 / 56033
• HGNCID: 955
• Length: 254
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 70/268 - (26%)
• Similarity: 98/268 - (36%)
• Gaps: 73/268 - (27%)

  Fly   101 PTSLRFNPIYPDPA---------SLFYQQVLQLQKNPSLFMPHFQAAA--------VAAAAAVQP 148
            |.:.||.|  |:..         |...:::|.....|....|...|||        |.|..|.:|
Human     7 PGAARFGP--PEGCADHRPHRYRSFMIEEILTEPPGPKGAAPAAAAAAAGELLKFGVQALLAARP 69

  Fly   149 ------TAYCDQYSPF-----TMDCEGFPNPASAAAALYCNAYPAASFYM-------------SN 189
                  ....:|.:.|     .:.|.|..:...||......|..|....:             ..
Human    70 FHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLAAGPGLPGAAGAPHLPLELQLRGKLEAAGPGE 134

  Fly   190 FGVK-RKGGQIR--FTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRR 251
            .|.| :||.:.|  ||..|...||.||...||||..:|..||..|.|:..|||||:||||.||::
Human   135 PGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 199

  Fly   252 ANLSKRSASAQGPIAGAAVGSPSS----ASSSSVPVLNLGSGSRCGQQSDEEDRMYLSEDDEDDD 312
            ..|.           |..:.||:.    ...:|:|.         .:|..|::|   ::|.|...
Human   200 IVLQ-----------GGGLESPTKPKGRPKKNSIPT---------SEQLTEQER---AKDAEKPA 241

  Fly   313 EDEGEADE 320
            |..||..:
Human   242 EVPGEPSD 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	28/52 (54%)
BARX1	NP_067545.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		5/14 (36%)
		Homeodomain	143..199	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..254		13/58 (22%)