Protein Alignment HHEX and en1b

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001013516.1
• Gene: en1b / 541371
• ZFINID: ZDB-GENE-980526-6
• Length: 274
• Species: Danio rerio
• Alignment Length: 284
• Identity: 69/284 - (24%)
• Similarity: 116/284 - (40%)
• Gaps: 74/284 - (26%)

  Fly    19 EQKSSSHRSQSRRGSSQS-PVAVTAGIATPHALAMPKASLA---------------------TGS 61
            |||     .|:.|.|::| .|:::..|.:|..|....|..|                     .||
Zfish     3 EQK-----DQNSRDSTESESVSLSPNIPSPPILPHQAAQQAHRTTNFFIDNILRPDFGCKKDPGS 62

  Fly    62 SSAAPTPSPSSATNIYDL----SREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVL 122
            ...|.|   |...|:..:    |..::..|.:..|.||::..:.:|         |:|
Zfish    63 RDRAQT---SGRENVNPMVIRPSHNSSLCQDSNCSSDSTSSSSSSS---------PSS------- 108

  Fly   123 QLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAA------AALYCNAY- 180
               |..|  :.||:.....||...:.|.     |...::..|...||..:      |.:||..|
Zfish   109 ---KQSS--VKHFEGNGSTAARNGENTP-----SIMMVNANGGTPPAKESQPLLWPAWVYCTRYS 163

  Fly   181 --PAASFYMSNFGVKR-----KGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQV 238
              |::.........|:     |..:..||::|.:.|:|.|.:::|::.:.|:.||.:|.|.:.|:
Zfish   164 DRPSSGPRTRKLKKKKSEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQSLAQELNLNESQI 228

  Fly   239 KTWFQNRRAKWRRANLSKRSASAQ 262
            |.||||:|||.::|:..|...:.|
Zfish   229 KIWFQNKRAKIKKASGYKNGLALQ 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	21/50 (42%)
en1b	NP_001013516.1	Homeodomain	186..241	CDD:459649	21/54 (39%)
		Engrail_1_C_sig	242..272	CDD:431338	3/11 (27%)