Protein Alignment HHEX and nkx3.3

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001013342.2
• Gene: nkx3.3 / 503746
• ZFINID: ZDB-GENE-050306-27
• Length: 240
• Species: Danio rerio
• Alignment Length: 310
• Identity: 72/310 - (23%)
• Similarity: 105/310 - (33%)
• Gaps: 117/310 - (37%)

  Fly     7 SSKAAFSIENILEQ-----KSSS----HRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSS 62
            :::.:|||.|||.|     |:.|    :..:.|...|.|.|.|..|
Zfish     3 NNRTSFSIHNILNQGHECGKNGSFDEEYEGEKRTQDSGSSVPVNRG------------------- 48

  Fly    63 SAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKN 127
                  :.|:.|.|                  ||.||...||..:....:..|......|:.:.:
Zfish    49 ------AESAQTRI------------------SSCVLVLESLSSDQHSCEEESTGEDNSLERRHD 89

  Fly   128 PSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFGV 192
            ..:                      ||..|                       .:.||..||...
Zfish    90 HEM----------------------DQQKP-----------------------QSCSFEDSNPKS 109

  Fly   193 KRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKR 257
            .:|..:..|:..|...||.||...:|||..||..||..||||:.|||.||||||.|.:|..::..
Zfish   110 SKKRSRAAFSHAQVYELERRFNLQRYLSGPERADLAGALKLTETQVKIWFQNRRYKTKRRQMAAE 174

  Fly   258 SASAQGPIAGAAVGSPSSASSSSVPVLNLGSGSRCGQQSDEEDRMYLSED 307
            .|:           :|::..:..|.|..|       .::|:  |.|.:||
Zfish   175 LAT-----------TPTTTLAKRVAVKVL-------VRNDQ--RQYNTED 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	27/50 (54%)
nkx3.3	NP_001013342.2	Homeodomain	112..168	CDD:459649	28/55 (51%)