Protein Alignment HHEX and E5

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_524825.1
• Gene: E5 / 45396
• FlyBaseID: FBgn0008646
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 394
• Identity: 104/394 - (26%)
• Similarity: 146/394 - (37%)
• Gaps: 100/394 - (25%)

  Fly     4 ATKSSKAAFSIENILEQKSSSHRSQSRRGS--------SQSPVAVT----AGIATPHALAMPK-- 54
            |:...|.||||::|:.:  ||.||...|.|        |:||.:.|    :|..||......:
  Fly    44 ASSKPKLAFSIDSIVGE--SSTRSAPLRVSVISSPPPRSESPASPTNTNNSGRRTPRGYIYCRRR 106

  Fly    55 ----ASLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLA--PTSLRFNPIYPDP 113
                .|.:...|..:.:|||.:|      ....|||....||.|.|:...  ||.:|..|:....
  Fly   107 DSLDRSRSPQRSPVSRSPSPPNA------GGNPAAAGNTAKSGDPSSGTGNPPTLIRPLPLPAPN 165

  Fly   114 ASLFYQQV--------LQLQKNPSLFMPHFQAAAVAAAAAV------QPTAYCDQYSPF-TMDCE 163
            .:|...:.        :....:|....|.|.||....|||:      |......|..|. |....
  Fly   166 LALIGNRTSPNAMAVRMAGPPHPPSQPPPFLAAQFQMAAALAHHHQQQQQQQQQQLPPVPTGPPH 230

  Fly   164 G--------------FP-------------NPASAAAALYCNAYPAASFYMSNFG---------- 191
            |              ||             :|..:|..|..::||...:.:|..|
  Fly   231 GPHPHLPPGQIPLGIFPGGPHPGHPPPHGHHPFGSAPHLIRDSYPLYPWLLSRHGRIFPRFPGNF 295

  Fly   192 ---VKRKGGQIR--FTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRR 251
               ..||..::|  |:..|...||..|..:.|:...||:.||..|.||:.|||.||||||.|.:|
  Fly   296 LFQPFRKPKRVRTAFSPTQLLKLEHAFEGNHYVVGAERKQLAQGLSLTETQVKVWFQNRRTKHKR 360

  Fly   252 ANLSKRSASAQGPIAGAAVGSPSSASSSSVPVLNLGSGSRCGQQSDEEDRMYLSEDDEDDDEDEG 316
            ....          .|....:.|:..|||.     |.|...|:...:.|....|.:|.:|.|||.
  Fly   361 MQQE----------GGDGSDTKSNKGSSSG-----GGGGGDGEDDAKHDGSQHSYEDAEDPEDED 410

  Fly   317 EADE 320
            |.:|
  Fly   411 EIEE 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/52 (46%)
E5	NP_524825.1	Homeodomain	304..360	CDD:459649	24/55 (44%)