Protein Alignment HHEX and Hmx

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001262674.1
• Gene: Hmx / 42110
• FlyBaseID: FBgn0264005
• Length: 718
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 97/476 - (20%)
• Similarity: 153/476 - (32%)
• Gaps: 194/476 - (40%)

  Fly    11 AFSIENILEQKSSSHRS-------------QSRRGSSQSPVAVT--------AGIATPHALAMPK 54
            :|||.:||.:...:.::             |...|..|....::        ..:|..:|...|.
  Fly   233 SFSISSILSRSEPAKKNGAAGLITPIPQLPQPGAGGPQDAAMLSRLGFISQWGALAGRYAALCPP 297

  Fly    55 A----------------SLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTS 103
            .                |.:|.::...|:|:..|..|..:.|...|::..|.||        |:.
  Fly   298 GWPWAPQRLPFHSPTHDSSSTNTTENPPSPTSMSPNNNNNNSNTTASSNQASKS--------PSH 354

  Fly   104 LRFNPIY-PDPASLFYQQVLQLQKNPSLFM---------PHFQAAAVAAAAAVQPTAYCDQYSPF 158
            ...:|:| |..:....||..|.|::|....         ||            |||      :|.
  Fly   355 HPLHPLYHPLGSQQQQQQQQQHQQHPQQQQHPQQQQQQHPH------------QPT------TPT 401

  Fly   159 TMDCEG-------FPNP---ASAAAALYCNAYPAASFYMSNFG---------------------- 191
            :....|       .|:|   .|....|    .|::|......|
  Fly   402 SSSSSGGGSSLTHHPHPHLTGSHGGYL----LPSSSNESDEEGEEIIEEDDGTDGPSDSSSPHGD 462

  Fly   192 ---VKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRR-- 251
               .::|..:..|:..|...||:.|...:|||..||..||..|:||:.|||.||||||.||:|
  Fly   463 GNSKRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLRLTETQVKIWFQNRRNKWKRQL 527

  Fly   252 ------ANLSKRSASAQ-----------GPIAGAAVGSP---------SSASSSS---VPVLNLG 287
                  ||::..:.:||           |..||.....|         ::|.::|   .|:.:|.
  Fly   528 AAELEAANMANMAHAAQRLVRVPVLYHDGTTAGFVPPPPPHHHPMQYYAAARNTSPPRPPLSSLV 592

  Fly   288 SGSRC---------------------------------------------GQQSD-EEDRMYLSE 306
            .|..|                                             ...|| |::|.::.:
  Fly   593 XGVGCLATAPMSLLKPPNSMAHPPHPQPPPPAPLHMQQRSFLGCEQLTETDMDSDSEQERSHMMD 657

  Fly   307 D-----DEDDDEDEGEADETP 322
            |     |.:.||::..|...|
  Fly   658 DEDAAIDVEADEEQESASPVP 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	26/50 (52%)
Hmx	NP_001262674.1	Homeodomain	469..525	CDD:459649	27/55 (49%)