Protein Alignment HHEX and msx2

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: XP_002936749.1
• Gene: msx2 / 394987
• XenbaseID: XB-GENE-852974
• Length: 256
• Species: Xenopus tropicalis
• Alignment Length: 286
• Identity: 65/286 - (22%)
• Similarity: 93/286 - (32%)
• Gaps: 99/286 - (34%)

  Fly     2 DIATKSSKAAFSIENILEQKSSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAP 66
            |...|.|...||:|.::..|.....:...||     |..:|..:||..|.|          ....
 Frog    28 DHKIKVSSLPFSVEALMADKRVPKEAPHLRG-----VDASAAGSTPRHLHM----------GIRD 77

  Fly    67 TPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSLF 131
            :|||...|..::.|        ::||.:|..  ..|..:....|..|..........|:|:.:
 Frog    78 SPSPPGLTKTFETS--------SVKSENSED--GTTWSKDGGSYSPPPRHLSPSTCTLRKHKT-- 130

  Fly   132 MPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFGVKRKG 196
                                                          |..|
 Frog   131 ----------------------------------------------NRKP--------------- 134

  Fly   197 GQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRR---ANLSKRS 258
             :..||:.|...||.:|...:|||..||...:..|.||:.|||.||||||||.:|   |.:.|..
 Frog   135 -RTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAEIEKLK 198

  Fly   259 ASAQGPIAGAA------VGSPSSASS 278
            .:|: ||....      :.||..|:|
 Frog   199 MAAK-PILPPGFSIPFPINSPIQAAS 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	25/50 (50%)
msx2	XP_002936749.1	Homeodomain	132..188	CDD:459649	26/71 (37%)