Protein Alignment HHEX and Noto

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001007473.1
• Gene: Noto / 384452
• MGIID: 3053002
• Length: 240
• Species: Mus musculus
• Alignment Length: 268
• Identity: 64/268 - (23%)
• Similarity: 105/268 - (39%)
• Gaps: 68/268 - (25%)

  Fly    31 RGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPSPSSATNIYDLSREAAAAQY-AMKSMD 94
            ||..:|..:|.|.:|.|....:...||...:.::              |:...|.:|| .:..:.
Mouse    33 RGRLESSFSVEAILARPKTRELAATSLPLSTCTS--------------LNLLGAVSQYGVLPWVC 83

  Fly    95 SSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYC---DQYS 156
            |:....|..|... :||         :..:...|.|.:.|.|.......:.:   .||   .:::
Mouse    84 STGSWLPAYLSVG-VYP---------LCSMSCVPGLNVTHHQQGLRLTGSEL---PYCLGPLKWA 135

  Fly   157 PFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFGVKRKGGQIR--FTSQQTKNLEARFASSKYL 219
            | |:|                         :.:.|.:|...::|  |..||.:.||..||....|
Mouse   136 P-TVD-------------------------LRDHGTERHTKRVRTTFNLQQLQELEKVFAKQHNL 174

  Fly   220 SPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKRSASAQGPIAGAAVGSPSSASSSSVPV- 283
            ..:||..||.:|.||:.||:.||||||.|:::....|..:|       :.:..|||:|..::..
Mouse   175 VGKERAQLAARLHLTENQVRIWFQNRRVKYQKQQKLKLPSS-------SVMEEPSSSSDGNIQSE 232

  Fly   284 -LNLGSGS 290
             ..||.||
Mouse   233 DAELGIGS 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	25/52 (48%)
Noto	NP_001007473.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Homeodomain	150..206	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..240		8/38 (21%)