Protein Alignment HHEX and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: XP_038962557.1
• Gene: Nkx2-4 / 366213
• RGDID: 1304985
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 297
• Identity: 80/297 - (26%)
• Similarity: 109/297 - (36%)
• Gaps: 62/297 - (20%)

  Fly    22 SSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPSPSSATNIYDLSREAAAA 86
            ::::|:.....|||:  |..||:..|||:|...|:.|..:::||                .||||
  Rat    44 AAAYRAPPTGPSSQA--AAVAGMQPPHAMAGHNAAAAAAAAAAA----------------AAAAA 90

  Fly    87 QYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSL----FMPHFQAAAVAAAAAVQ 147
            .|.|                    |...|.|....:....|..|    .:|.:.......|||..
  Rat    91 TYHM--------------------PPGVSQFPHSAMGSYCNGGLGNMGELPAYTDGMRGGAAAAA 135

  Fly   148 PTAYCDQYSPFTMDCEGFPNPASAA-----AALYCNAYPAASFYMSNFGVKRKGGQIRFTSQQTK 207
            ...|.....|.......|..|::..     .:|...|..|.|....:....|:..::.|:..|..
  Rat   136 TGWYGANTDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLAPLHAAAPRRKRRVLFSQAQVY 200

  Fly   208 NLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKRSASAQ--GPIAGAAV 270
            .||.||...||||..||.|||..:.||..|||.||||.|.|.:|....|.:...|  |.:.....
  Rat   201 ELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPPP 265

  Fly   271 GSPSSASSSSVPVLNLGSGSRC------------GQQ 295
            ..|.|....:|||| :..|..|            |||
  Rat   266 PPPPSPRRVAVPVL-VKDGKPCQNGAGTPTPGQGGQQ 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	26/50 (52%)
Nkx2-4	XP_038962557.1	Homeodomain	188..244	CDD:459649	26/55 (47%)