Protein Alignment HHEX and Hoxd12

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001178832.1
• Gene: Hoxd12 / 366082
• RGDID: 1309797
• Length: 268
• Species: Rattus norvegicus
• Alignment Length: 271
• Identity: 60/271 - (22%)
• Similarity: 101/271 - (37%)
• Gaps: 68/271 - (25%)

  Fly    18 LEQKSSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPS-PSSATNIYDLSR 81
            |:...|.:.|..|...||        :|....::.|:::|...::.|:.||: |::|
  Rat    18 LQSPDSFYFSNLRPNGSQ--------LAALPPISYPRSALPWAATPASCTPAQPTTA-------- 66

  Fly    82 EAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAV 146
             :|...::...:..|..:...|........|....:........:..|...|.|...:....:|:
  Rat    67 -SAFGGFSQPYLTGSGPIGLQSPGTKDGPEDQVKFYTPDAATASEERSRTRPPFAPESSLVHSAL 130

  Fly   147 QPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFGVKRKG--------------- 196
            :.|.|         |..|....|..:..|...| |.|    |||....||
  Rat   131 KGTKY---------DFAGVGRAAPGSVTLLQGA-PCA----SNFKEDTKGPLNLNMAVQVAGVAS 181

  Fly   197 ----------------GQIR-----FTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKT 240
                            |:.|     :|.||...||..|..:::::.::|:.|:.:|.|:|:|||.
  Rat   182 CLRSSLPDGLPWGAAPGRARKKRKPYTKQQIAELENEFLVNEFINRQKRKELSNRLNLSDQQVKI 246

  Fly   241 WFQNRRAKWRR 251
            ||||||.|.:|
  Rat   247 WFQNRRMKKKR 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	22/55 (40%)
Hoxd12	NP_001178832.1	Homeodomain	201..257	CDD:459649	22/55 (40%)