Protein Alignment HHEX and Hlx

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001071142.1
• Gene: Hlx / 364069
• RGDID: 1311961
• Length: 476
• Species: Rattus norvegicus
• Alignment Length: 308
• Identity: 81/308 - (26%)
• Similarity: 117/308 - (37%)
• Gaps: 65/308 - (21%)

  Fly    30 RRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMK--- 91
            |.||.|.|.:.|.  ..||           .|.||   |:|||....:.:.| ..:|::..|
  Rat   142 RAGSLQPPTSGTR--VVPH-----------HSGSA---PAPSSKDLKFGIDR-ILSAEFDPKVKE 189

  Fly    92 ---SMDSSAVLA---PTSLRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAVAAAAAVQP-T 149
               ..|.:::|.   ||.:....:.|.....|           :...|..:|:|:.:..:..| .
  Rat   190 GNTLRDLTSLLTGGRPTGVHLAGLQPSAGQFF-----------ASLDPISEASAILSPLSSNPRN 243

  Fly   150 AYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFGVKRKGGQIRFTSQQTKNLEARFA 214
            :...|:.      :.||.|   .|.|..:..|      ..:..||...:..|::.|.|.||.||.
  Rat   244 SVQHQFQ------DTFPGP---YAVLTKDTMP------QTYKRKRSWSRAVFSNLQRKGLEKRFE 293

  Fly   215 SSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWR-----RANLSKRSASAQGPIAGA-AVGSP 273
            ..||::..:|:.||..|.|||.|||.||||||.|||     :|...|...:.:.|..|. |.|..
  Rat   294 IQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGVPAEGER 358

  Fly   274 SSASSSSVPVLNLGSGSRCGQQSDEEDRMYLSEDDEDDDEDEGEADET 321
            ...|.|.      ..|....:.||.|.......|.|..:..|....:|
  Rat   359 EERSPSR------SEGEAESESSDSESLDMAPSDTERTEGTERSLHQT 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	28/55 (51%)
Hlx	NP_001071142.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..170		15/43 (35%)
		Homeodomain	270..330	CDD:459649	29/59 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..401		18/79 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..476