Protein Alignment HHEX and cad

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Alignment Length: 297
• Identity: 68/297 - (22%)
• Similarity: 105/297 - (35%)
• Gaps: 64/297 - (21%)

  Fly     7 SSKAAFSIENI------LEQKSSSHRSQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSS--- 62
            ||.|...::|:      |.|:...|.:.:...|:.|..:.:.|......|....:|:..|.:
  Fly    88 SSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGG 152

  Fly    63 ---SAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQL 124
               ..|....|.||...:.        |:..:.:.|..:....|...:|..|..||
  Fly   153 GGVGGATDGGPGSAPPNHQ--------QHIAEGLPSPPITVSGSEISSPGAPTSAS--------- 200

  Fly   125 QKNPSLFMPHFQAA-AVAAAAAVQPTAYCDQYSPFTMDCEGFPNP------ASAAAALYCN---- 178
                   .||...| .::|.|........:..||.|.:.....|.      .|.:...|.:
  Fly   201 -------SPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKK 258

  Fly   179 -AYPA--------------ASFYMSNFGVKRKGGQIR--FTSQQTKNLEARFASSKYLSPEERRH 226
             ||||              .|..:...|..|...:.|  :|..|...||..:.:|:|::...:..
  Fly   259 PAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSE 323

  Fly   227 LALQLKLTDRQVKTWFQNRRAKWRRANLSKRSASAQG 263
            ||..|.|::||||.||||||||.|:.|......:..|
  Fly   324 LAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMG 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	23/52 (44%)
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	23/54 (43%)