Protein Alignment HHEX and hlx1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001418073.1
• Gene: hlx1 / 327096
• ZFINID: ZDB-GENE-030131-5304
• Length: 357
• Species: Danio rerio
• Alignment Length: 335
• Identity: 88/335 - (26%)
• Similarity: 129/335 - (38%)
• Gaps: 72/335 - (21%)

  Fly     9 KAAFSIENILE-------QKSSS---H---RSQSRRGSSQSPVAVTAGIATPHALAMPKASLATG 60
            |.:|.|.:||.       |.|||   |   |:|..  ||.||:..:.  .||.|...| |.|..|
Zfish    32 KPSFCIADILHVGDAENIQGSSSLMAHIGARAQVH--SSGSPLRPSP--VTPDARLHP-AYLRHG 91

  Fly    61 ----SSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSL----RFNPIYPDPASLF 117
                |.:|...|.|:|....:.:.| ..:..:..||.:|.::...||:    |.:.::...:..|
Zfish    92 IHLTSRAAINAPPPTSKDLKFGIDR-ILSTDFEPKSKESPSLRDLTSIVSPNRQSAVHVSASPYF 155

  Fly   118 YQQVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPA 182
            ......:.:..||......||..:.....|.|.                 |....|.|..:..|
Zfish   156 ASIDPTMSETSSLMGSIGNAARQSGQHQFQDTF-----------------PGRPYAVLSKDTMP- 202

  Fly   183 ASFYMSNFGVKRKGGQIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRA 247
                 ..:..||...:..|::.|.|.||.||...||::..:|:.||..|.|||.|||.||||||.
Zfish   203 -----QTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRM 262

  Fly   248 KWRRAN--LSKRSASAQGPIAGAAVGSPSSASSSSVPVLNLGSGSRCGQQSDEEDRMYLSEDD-E 309
            |||.:.  .:::....:.|...||.....                   ::.|.|.....||.: |
Zfish   263 KWRHSKEAQAQKDKEKEQPDKSAAETEQK-------------------ERDDSECETEPSESEFE 308

  Fly   310 DDDEDEGEAD 319
            |..||:.:.|
Zfish   309 DGPEDKSDVD 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	27/50 (54%)
hlx1	NP_001418073.1	Homeodomain	206..266	CDD:459649	29/59 (49%)