Protein Alignment HHEX and HOXD1

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 82/313 - (26%)
• Similarity: 114/313 - (36%)
• Gaps: 92/313 - (29%)

  Fly    45 ATPHALAMPKASLATGS---------SSAAPTPSPSSATNIYDLSREA----AAAQYAMKSMDSS 96
            |.|.|| .|...|..|.         ::|.|:|||.:|.     :|.:    ||.|||..:::.:
Human    32 ARPVAL-QPAFPLGNGDGAFVSCLPLAAARPSPSPPAAP-----ARPSVPPPAAPQYAQCTLEGA 90

  Fly    97 --AVLAPTS---------LRFNPIYPDPASLFYQQVLQLQKNPSLFMPHFQAAAV---------- 140
              ...||.:         |...|.|..|.      ||....:......|:..:||
Human    91 YEPGAAPAAAAGGADYGFLGSGPAYDFPG------VLGRAADDGGSHVHYATSAVFSGGGSFLLS 149

  Fly   141 -----AAAAAVQPTAYCDQYSPFTMDCEGFP---NPASAAAALY------CNAYPAASFYMSNFG 191
                 ||.....|...|.:.|     .:|.|   ..||.|...|      .:..|||........
Human   150 GQVDYAAFGEPGPFPACLKAS-----ADGHPGAFQTASPAPGTYPKSVSPASGLPAAFSTFEWMK 209

  Fly   192 VKR---KGGQI--------------RFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVK 239
            |||   |.|::              .|:::|...||..|..:|||:...|..:|..|.|.|.|||
Human   210 VKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVK 274

  Fly   240 TWFQNRRAKWRRANLSKRSASA------QGPIAGAA----VGSPSSASSSSVP 282
            .||||||.|.::.......|:|      |.|::|..    :.:|.|.|.|..|
Human   275 IWFQNRRMKQKKREREGLLATAIPVAPLQLPLSGTTPTKFIKNPGSPSQSQEP 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	23/50 (46%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		0/4 (0%)
		Homeodomain	233..286	CDD:459649	23/52 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328		7/23 (30%)