Protein Alignment HHEX and HOXC9

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_008828.1
• Gene: HOXC9 / 3225
• HGNCID: 5130
• Length: 260
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 63/235 - (26%)
• Similarity: 100/235 - (42%)
• Gaps: 46/235 - (19%)

  Fly    58 ATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDP---ASLFYQ 119
            |||:..||..|| ....:..|....:.|.:.|:.|...:.|.:.:|:.::|..|.|   |...|.
Human    30 ATGAHPAAARPS-GLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTRYM 93

  Fly   120 QVLQLQKNPSLFMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDC---EG--FPN------------ 167
            :......:.::..|.|.|.  ....|::|.||..:.:    ||   ||  :|:
Human    94 RTWLEPLSGAVSFPSFPAG--GRHYALKPDAYPGRRA----DCGPGEGRSYPDYMYGSPGELRDR 152

  Fly   168 -----PASAAAALYCNAY-----------PAASFYMSNFGVKRKGGQIRFTSQQTKNLEARFASS 216
                 |:..|.||..:.:           |.|::..:....|::   ..:|..||..||..|..:
Human   153 APQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKR---CPYTKYQTLELEKEFLFN 214

  Fly   217 KYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSK 256
            .||:.:.|..:|..|.||:||||.||||||.|.::.|..|
Human   215 MYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEK 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/50 (48%)
HOXC9	NP_008828.1	Hox9_act	1..179	CDD:461369	34/155 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..181		12/64 (19%)
		Homeodomain	193..241	CDD:459649	19/50 (38%)