Protein Alignment HHEX and HOXC4

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 65/235 - (27%)
• Similarity: 98/235 - (41%)
• Gaps: 56/235 - (23%)

  Fly    66 PTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQKNPSL 130
            |.|.||                |..:....:::..|.:.|.:    .||...:...   :|:.||
Human    56 PPPRPS----------------YPERQYSCTSLQGPGNSRGH----GPAQAGHHHP---EKSQSL 97

  Fly   131 FMPHFQAAAVAAAAAVQPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYP-AASFYMSNFGVKR 194
            ..|...:.|.|:.:...|.  |.|.:|        .:|:|||:.... .|| ....::|......
Human    98 CEPAPLSGASASPSPAPPA--CSQPAP--------DHPSSAASKQPI-VYPWMKKIHVSTVNPNY 151

  Fly   195 KGGQIR-----FTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRR--- 251
            .||:.:     :|.||...||..|..::||:...|..:|..|.|::||:|.||||||.||::
Human   152 NGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHR 216

  Fly   252 -ANLSKRSASAQGPIAGAAVGSPSSA--------SSSSVP 282
             .|...|||    |.||||..:.|:|        |.|:.|
Human   217 LPNTKVRSA----PPAGAAPSTLSAATPGTSEDHSQSATP 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	23/55 (42%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		22/106 (21%)
		Antp-type hexapeptide	135..140		2/4 (50%)
		Homeodomain	157..213	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		14/43 (33%)