Protein Alignment HHEX and HOXB8

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 69/307 - (22%)
• Similarity: 108/307 - (35%)
• Gaps: 85/307 - (27%)

  Fly    27 SQSRRGSSQSPVAVTAGIATPHALAMPKASLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMK 91
            |:.:.|.|..|.....|.|....   .:.::..|.||......||.....|......:.|.|..
Human    11 SKYKTGESLRPNYYDCGFAQDLG---GRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQ- 71

  Fly    92 SMDSSAVLAPTSLRFNP----IYPDPASLFYQQVLQLQKNPSLF------MPHFQAAAVAAAAAV 146
                           ||    .:.||.:.:....||.|   |||      :..:....:|||:.:
Human    72 ---------------NPCAVACHGDPGNFYGYDPLQRQ---SLFGAQDPDLVQYADCKLAAASGL 118

  Fly   147 QPTAYCDQYSPFTMDCEGFPNPASAAAALYCNAYPAASFYMSNFGVKRKGGQIRFTSQQTKNLEA 211
            ...|...:.||.......:..|.:||.                    |:.|:..::..||..||.
Human   119 GEEAEGSEQSPSPTQLFPWMRPQAAAG--------------------RRRGRQTYSRYQTLELEK 163

  Fly   212 RFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKRSASAQGPIAGAAVGSPSSA 276
            .|..:.||:.:.|..::..|.||:||||.||||||.||::.|...:..|
Human   164 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPS---------------- 212

  Fly   277 SSSSVPVLNLGSGSRCGQQSDEEDRMYLSEDDEDDDEDEGEADETPK 323
                         |:|.|:..|:.::    :...:..|||:|.:..|
Human   213 -------------SKCEQEELEKQKL----ERAPEAADEGDAQKGDK 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	23/50 (46%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		0/4 (0%)
		Homeodomain	147..203	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		11/73 (15%)