Protein Alignment HHEX and HOXA9

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_689952.1
• Gene: HOXA9 / 3205
• HGNCID: 5109
• Length: 272
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 62/279 - (22%)
• Similarity: 92/279 - (32%)
• Gaps: 103/279 - (36%)

  Fly    40 VTAGIATPHALAMPKASLATGSSSAAPTPSPSSATNIYDLSREAAAAQYAMKSMDSSAVLAPTSL 104
            ::.|...|..|..|....||  .:..|..||.                    |..|.|.:...|
Human    25 LSVGRYAPGTLGQPPRQAAT--LAEHPDFSPC--------------------SFQSKATVFGAS- 66

  Fly   105 RFNPIYPD-----PASLFYQQVLQLQKNPSLFMPHFQAAAVAAA-------AAVQPTAYCDQYSP 157
             :||::..     ||::::..    ..:|.:   |.||...|||       :.::||       |
Human    67 -WNPVHAAGANAVPAAVYHHH----HHHPYV---HPQAPVAAAAPDGRYMRSWLEPT-------P 116

  Fly   158 FTMDCEGFPN---------PASAAAA--------------LYCNA-------YPAASFYMSNFGV 192
            ..:...|.|:         |.||...              ..|.:       .|:...:..|...
Human   117 GALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFSENNAE 181

  Fly   193 KRKGG-----------------------QIRFTSQQTKNLEARFASSKYLSPEERRHLALQLKLT 234
            ...||                       :..:|..||..||..|..:.||:.:.|..:|..|.||
Human   182 NESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLT 246

  Fly   235 DRQVKTWFQNRRAKWRRAN 253
            :||||.||||||.|.::.|
Human   247 ERQVKIWFQNRRMKMKKIN 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/50 (48%)
HOXA9	NP_689952.1	Hox9_act	1..193	CDD:461369	37/205 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..198		5/42 (12%)
		Homeodomain	207..263	CDD:459649	24/55 (44%)