Protein Alignment HHEX and HOXA7

DIOPT Version :10

• Sequence 1: NP_650938.2
• Gene: HHEX / 42495
• FlyBaseID: FBgn0038852
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_008827.2
• Gene: HOXA7 / 3204
• HGNCID: 5108
• Length: 230
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 76/246 - (30%)
• Similarity: 104/246 - (42%)
• Gaps: 37/246 - (15%)

  Fly    80 SREAAAAQYAMKSMDSSAVLAPTSLRFNPIYPDPASLFYQQVLQLQK-NPSLFMPHFQAAAVAAA 143
            |:..|.|.....:..:|...||.|.|..  |...|..|...|..|.. |..|:...|.:.....|
Human    12 SKYTAGASLFQNAEPTSCSFAPNSQRSG--YGAGAGAFASTVPGLYNVNSPLYQSPFASGYGLGA 74

  Fly   144 AAV--QPTAYCDQYSPFTMD------CEGFPNPA-SAAAALYCNAYPAASFYMSNFGVKRKGGQI 199
            .|.  .|.|..||..|....      |:.....| ..||......||    :|.:.|..||.|:.
Human    75 DAYGNLPCASYDQNIPGLCSDLAKGACDKTDEGALHGAAEANFRIYP----WMRSSGPDRKRGRQ 135

  Fly   200 RFTSQQTKNLEARFASSKYLSPEERRHLALQLKLTDRQVKTWFQNRRAKWRRANLSKRSASAQGP 264
            .:|..||..||..|..::||:...|..:|..|.||:||:|.||||||.||      |:....:||
Human   136 TYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKW------KKEHKDEGP 194

  Fly   265 IAGAAVGSPSSASSSSVPVLNLGSGSRCGQQSDEEDRMYLSEDDEDDDEDE 315
            .|.||   |..|..|:       :.:....::||||     :|:|::||:|
Human   195 TAAAA---PEGAVPSA-------AATAAADKADEED-----DDEEEEDEEE 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HHEX	NP_650938.2	Homeodomain	200..251	CDD:459649	24/50 (48%)
HOXA7	NP_008827.2	Antp-type hexapeptide	119..124		2/8 (25%)
		Homeodomain	131..187	CDD:459649	26/61 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..230		16/57 (28%)